Title:
METHOD FOR DETERMINING TUMOR SITE AND APPARATUS FOR DETERMINING TUMOR SITE
Document Type and Number:
WIPO Patent Application WO/2017/082242
Kind Code:
A1
Abstract:
The present invention realizes a method and a device with which it is possible to determine, more accurately than in the prior art, a tumor site from a sample that includes connective tissue including an autofluorescent substance. The present invention acquires: image data Ic that corresponds to the intensity distribution of light received via a filter Fc for transmitting light of wavelength band λc, which includes part of the wavelength band of fluorescence emitted by porphyrins, from among the light emitted by the sample; and image data Isi (i=1, 2,..., n) that corresponds to the intensity distribution of light received via a filter Fsi (i=1, 2,..., n) for transmitting light of wavelength band λsi (i=1, 2,..., n), which includes part of the wavelength band of fluorescence emitted by n types of autofluorescent substances, from among the light emitted by the sample. Calculations are then performed on the basis of the image data Ic and Isi, thereby generating image data Ip that corresponds to the intensity distribution of fluorescence emitted by porphyrins from among the light emitted by the sample.
Inventors:
KATO YOSHIYUKI (JP)
MINAMIKAWA TAKEO (JP)
TAKAMATSU TETSURO (JP)
HARADA YOSHINORI (JP)
MINAMIKAWA TAKEO (JP)
TAKAMATSU TETSURO (JP)
HARADA YOSHINORI (JP)
Application Number:
PCT/JP2016/083076
Publication Date:
May 18, 2017
Filing Date:
November 08, 2016
Export Citation:
Assignee:
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
USHIO ELECTRIC INC (JP)
USHIO ELECTRIC INC (JP)
International Classes:
G01N21/64; A61B10/00
Domestic Patent References:
| WO2016063949A1 | 2016-04-28 |
Foreign References:
| JP2011191271A | 2011-09-29 | |||
| US20100145416A1 | 2010-06-10 | |||
| JP2013024792A | 2013-02-04 | |||
| JP2012052985A | 2012-03-15 | |||
| US20100173350A1 | 2010-07-08 |
Other References:
ANDERSSON-ENGELS, S ET AL.: "Medical diagnostic system based on simultaneous multispectral fluorescence imaging", APPLIED OPTICS, vol. 33, no. 34, 1 December 1994 (1994-12-01), pages 8022 - 8029, XP002585671
TETSUO FURUYA ET AL.: "Autofluorescence of Bronchial Tissue", THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE, vol. 17, no. 1, March 1996 (1996-03-01), pages 75 - 80, XP055381390
HARADA, K ET AL.: "Detection of Lymph Node Metastases in Human Colorectal Cancer by Using 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence with Spectral Unmixing", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 14, 21 November 2013 (2013-11-21), pages 23140 - 23152, XP055381394, ISSN: 1422-0067
TETSUO FURUYA ET AL.: "Autofluorescence of Bronchial Tissue", THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE, vol. 17, no. 1, March 1996 (1996-03-01), pages 75 - 80, XP055381390
HARADA, K ET AL.: "Detection of Lymph Node Metastases in Human Colorectal Cancer by Using 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence with Spectral Unmixing", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 14, 21 November 2013 (2013-11-21), pages 23140 - 23152, XP055381394, ISSN: 1422-0067
Attorney, Agent or Firm:
UNIUS PATENT ATTORNEYS OFFICE (JP)
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