METHOD AND DEVICE FOR ANALYZING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) TYPES

Title:

METHOD AND DEVICE FOR ANALYZING MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) TYPES

Document Type and Number:

WIPO Patent Application WO/2023/158080

Kind Code:

A1

Abstract:

Disclosed is a computer program stored in a computer-readable storage medium. The computer program, when executed by at least one processor of a computing device, enables the at least one processor to perform a method for determining the relative expression ratio correlation between MHC types. The method may comprise the steps of: obtaining a list of peptide sequences from a biological sample, comprising an MHC-peptide conjugate, derived from at least one specimen; clustering the list of peptide sequences by using a clustering model; and determining the relative expression ratio correlation between the MHC types on the basis of the clustering.

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Inventors:

SONG SUNGJAE (KR)
LEE IN WON (KR)
SEO JEONG HAN (KR)
LIM CHAE LYUL (KR)

Application Number:

PCT/KR2022/020526

Publication Date:

August 24, 2023

Filing Date:

December 16, 2022

Export Citation:

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Assignee:

NEOGENTC CORP (KR)

International Classes:

G01N33/68; G01N33/569; G16B25/10; G16B40/30

Foreign References:

US20190346442A1	2019-11-14
US11231419B2	2022-01-25
JP2013529472A	2013-07-22
KR20200109471A	2020-09-23

Other References:

ANDREATTA MASSIMO, LUND OLE, NIELSEN MORTEN: "Simultaneous alignment and clustering of peptide data using a Gibbs sampling approach", BIOINFORMATICS, OXFORD UNIVERSITY PRESS , SURREY, GB, vol. 29, no. 1, 1 January 2013 (2013-01-01), GB , pages 8 - 14, XP093085185, ISSN: 1367-4803, DOI: 10.1093/bioinformatics/bts621

Attorney, Agent or Firm:

LEE, Dae Ho et al. (KR)

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