METHOD AND DEVICE FOR MASS SPECTROMETRY

WIPO Patent Application WO/2014/119496

A1

This device for mass spectrometry is equipped with a liquid specimen supply part which sends a liquid specimen sandwiched between bubbles, an ion source part which ionizes the specimen, and a mass spectrometry part in which the ions generated in the ion source part are separated in accordance with mass and detected. The device is characterized in that the ion source part is configured so as to include a liquid supply tube (305) which is for transporting a specimen from the liquid specimen supply part, a degassing/liquid retention part (307) in which bubbles (302) are removed, a spraying part (306) which ionizes the specimen, and a high-voltage power supply part (309) which applies a high voltage to the spraying part (306). The device is further characterized in that after removing the bubbles (302) (308), a Taylor cone is formed from the resultant pre-solution (303), and the specimen is ionized thereafter. Thus, the ionization of an intended specimen is stabilized, and the measurement reproducibility is improved.

YASUDA HIROYUKI (JP)
ITO SHINYA (JP)
FUJII AKIRA (JP)
TERUI YASUSHI (JP)

PCT/JP2014/051610

August 07, 2014

January 27, 2014

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HITACHI HIGH TECH CORP (JP)

G01N27/62

WO2003065405A1

2003-08-07

JPS6232365A

1987-02-12

ATSUMU HIRABAYASHI: "Electro Spray ni Okeru Taylor Cone no Keisei", JOURNAL OF THE TEXTILE MACHINERY SOCIETY OF JAPAN, vol. 64, no. 11, 25 November 2011 (2011-11-25), pages 657 - 661

INOUE Manabu et al. (JP)
Manabu Inoue (JP)

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