Title:
METHOD FOR DIAGNOSIS OF NEUROPSYCHIATRIC DISEASE
Document Type and Number:
WIPO Patent Application WO/2008/013270
Kind Code:
A1
Abstract:
A method for measurement of a blood CRF level for use in the diagnosis of a neuropsychiatric disease, comprising the steps of: analyzing a blood collected from a mammal and calculating a CRF level in the blood; and comparing the calculated blood CRF level with the standard value for a blood CRF level.
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Inventors:
MATSUOKA SHOZO (JP)
FUNAKOSHI YOSUKE (JP)
IMAGAWA MASAYUKI (JP)
HATAKEYAMA KATSUTOSHI (JP)
WATANABE JUN (JP)
FUNAKOSHI YOSUKE (JP)
IMAGAWA MASAYUKI (JP)
HATAKEYAMA KATSUTOSHI (JP)
WATANABE JUN (JP)
Application Number:
PCT/JP2007/064786
Publication Date:
January 31, 2008
Filing Date:
July 27, 2007
Export Citation:
Assignee:
ONO PHARMACEUTICAL CO (JP)
MATSUOKA SHOZO (JP)
FUNAKOSHI YOSUKE (JP)
IMAGAWA MASAYUKI (JP)
HATAKEYAMA KATSUTOSHI (JP)
WATANABE JUN (JP)
MATSUOKA SHOZO (JP)
FUNAKOSHI YOSUKE (JP)
IMAGAWA MASAYUKI (JP)
HATAKEYAMA KATSUTOSHI (JP)
WATANABE JUN (JP)
International Classes:
G01N33/53; A61K45/00; A61P25/00; A61P25/24; G01N33/15; G01N33/50; G01N33/543
Other References:
XIA X. ET AL.: "Ethanolic Extracts from Curcuma longa Attenuates Behavioral, Immune, and Neuroendocrine Alterations in a Rat Chronic Mild Stress Model", BIOL. PHARM. BULL., vol. 29, no. 5, 1 May 2006 (2006-05-01), pages 938 - 944, XP003024601
SUZUKI S. ET AL.: "Somatostatin Analogue (SMS 201-995) Decreases Plasma Levels of Corticotropin (ACTH) and Corticotropin-Releasing Hormone in a Patient with Ectopic ACTH-Producing Tumors", ENDOCRINOLOGIA JAPONICA, vol. 37, no. 6, December 1990 (1990-12-01), pages 923 - 932, XP003024602
SHUSO SUEMARU ET AL.: "CEREBROSPINAL FLUID AND PLASMA CORTICOTROPIN-RELEASING HORMONE IN SENILE DEMENTIA", LIFE SCIENCES, vol. 48, no. 19, 1991, pages 1871 - 1879, XP003024600
BANKI C.M. ET AL.: "CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depression and Schizophrenia", THE AMERICAN JOURNAL OF PSYCHIATRY, vol. 144, no. 7, 1987, pages 873 - 877, XP003024603
MIHALY ARATO ET AL.: "Elevated CSF CRF in Suicide Victims", BIOLOGICAL PSYCHIATRY, vol. 25, no. 3, 1989, pages 355 - 359, XP022018857
SUZUKI S. ET AL.: "Somatostatin Analogue (SMS 201-995) Decreases Plasma Levels of Corticotropin (ACTH) and Corticotropin-Releasing Hormone in a Patient with Ectopic ACTH-Producing Tumors", ENDOCRINOLOGIA JAPONICA, vol. 37, no. 6, December 1990 (1990-12-01), pages 923 - 932, XP003024602
SHUSO SUEMARU ET AL.: "CEREBROSPINAL FLUID AND PLASMA CORTICOTROPIN-RELEASING HORMONE IN SENILE DEMENTIA", LIFE SCIENCES, vol. 48, no. 19, 1991, pages 1871 - 1879, XP003024600
BANKI C.M. ET AL.: "CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depression and Schizophrenia", THE AMERICAN JOURNAL OF PSYCHIATRY, vol. 144, no. 7, 1987, pages 873 - 877, XP003024603
MIHALY ARATO ET AL.: "Elevated CSF CRF in Suicide Victims", BIOLOGICAL PSYCHIATRY, vol. 25, no. 3, 1989, pages 355 - 359, XP022018857
Attorney, Agent or Firm:
IWATANI, Ryo (1-31 Dojima 2-chome, Kita-ku, Osaka-sh, Osaka 03, JP)
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