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Title:
METHOD FOR DISTINGUISHING BETWEEN MULTIPLE SCLEROSIS AND NEUROMYELITIS OPTICA SPECTRUM DISORDER
Document Type and Number:
WIPO Patent Application WO/2019/009446
Kind Code:
A1
Abstract:
The present invention relates to a composition for distinguishing between multiple sclerosis and neuromyelitis optica spectrum disorder, and a method for distinguishing between multiple sclerosis and neuromyelitis optica spectrum disorder using the composition. Specifically, the method of the present invention may clearly distinguish between multiple sclerosis and neuromyelitis optica spectrum disorder which have similar clinical features by measuring the concentrations of citric acid and lactic acid which are specific metabolites in cerebrospinal fluid and comparing said concentrations with the concentrations of citric acid and lactic acid in normal subjects, and therefore may be usefully used to diagnose multiple sclerosis and neuromyelitis optica spectrum disorder.

Inventors:
PARK, Sung Jean (#303-103, 29Haedoji-ro 84beon-gil,Yeonsu-gu, Incheon, 21996, KR)
KIM, Ho Jin (#606-1501, 22 Gajwa 2-ro,Ilsanseo-gu,Goyang-si, Gyeonggi-do, 10211, KR)
KIM, Hyun Hwi (#201, 25Gwanggyohosu-ro 378beon-gil,Suji-gu, Yongin-si Gyeonggi-do, 16940, KR)
Application Number:
KR2017/007193
Publication Date:
January 10, 2019
Filing Date:
July 05, 2017
Export Citation:
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Assignee:
GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (1342, Seongnam-daeroSujeong-gu,Seongnam-si, Gyeonggi-do, 13120, KR)
International Classes:
G01N33/48; G01N33/53
Attorney, Agent or Firm:
LEE, Won Hee (8th Fl. Sung-ji Heights II, 147 Teheran-ro,Gangnam-gu, Seoul, 06132, KR)
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