Title:
METHOD FOR DYNAMICALLY REMOVING RECOMBINANT HUMAN NERVE GROWTH FACTOR PRECURSOR BY HYDROPHOBIC INTERACTION CHROMATOGRAPHY
Document Type and Number:
WIPO Patent Application WO/2019/184366
Kind Code:
A1
Abstract:
Provided is a method for removing a recombinant human nerve growth factor precursor by using hydrophobic interaction chromatography characterized in that a washing step is added before elution, said washing step using a washing fluid reduced by a stage conductance and an organic solvent, in order to remove a precursor molecule variant.
Inventors:
LIU WENCHAO (CN)
SUN HONGLIANG (CN)
ZHANG YI (CN)
WANG YUESHENG (CN)
SUN HONGLIANG (CN)
ZHANG YI (CN)
WANG YUESHENG (CN)
Application Number:
PCT/CN2018/114508
Publication Date:
October 03, 2019
Filing Date:
November 08, 2018
Export Citation:
Assignee:
XINTRUM PHARMACEUTICALS LTD (CN)
International Classes:
C07K14/48; C07K1/20
Foreign References:
| CN108467429A | 2018-08-31 | |||
| CN108239146A | 2018-07-03 | |||
| CN106478801A | 2017-03-08 | |||
| CN103130868A | 2013-06-05 | |||
| CN1237184A | 1999-12-01 | |||
| CN103880943A | 2014-06-25 |
Attorney, Agent or Firm:
HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS (CN)
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