Title:
METHOD FOR EFFECTIVELY DELIVERING GENE INTO CELLS BY USING PHOTOTHERMAL EFFECT OF GOLD NANOPARTICLES
Document Type and Number:
WIPO Patent Application WO/2017/039074
Kind Code:
A1
Abstract:
The present invention relates to a method for effectively delivering an active material into cells by using the photothermal effect of gold nanoparticles and, more specifically, to a method for delivering a material into cells, comprising the steps of: a) forming a complex of a material, to be delivered into cells, and a liposome; and b) treating the cells with the complex and gold nanoparticles and irradiating near infrared rays thereat. According to the present invention, in the delivery of a bioactive material into cells, remarkably high efficiency of material delivery into cells is exhibited in comparison with that of a conventional method using a liposome complex, and thus gene therapy efficiency can be increased by facilitating gene delivery into cells.
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Inventors:
PARK JI HO (KR)
OH NURI (KR)
OH NURI (KR)
Application Number:
PCT/KR2015/013658
Publication Date:
March 09, 2017
Filing Date:
December 14, 2015
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
C12N15/88; C01G7/00
Domestic Patent References:
| WO2011116237A1 | 2011-09-22 | |||
| WO2012097255A2 | 2012-07-19 | |||
| WO2013095736A2 | 2013-06-27 |
Foreign References:
| KR101437885B1 | 2014-09-15 |
Other References:
HAN, GANG ET AL.: "Drug and Gene Delivery Using Gold Nanoparticles", NANOBIOTECHNOLOGY, vol. 3, no. 1, 26 April 2007 (2007-04-26), pages 40 - 45
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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