Title:
METHOD FOR EFFICIENT PRODUCTION OF INDUCED PLURIPOTENT STEM CELLS UTILIZING CELLS DERIVED FROM ORAL MUCOSA
Document Type and Number:
WIPO Patent Application WO/2011/024550
Kind Code:
A1
Abstract:
Disclosed is a technique which can produce induced pluripotent stem cells with high establishment efficiency and imposes lower burden on patients.
iPS cells can be produced efficiently with significantly increased establishment efficiency by selecting cells derived from the oral mucosa and introducing a reprogramming factor, which can induce the reprogramming of the cells into pluripotent stem cells, into the cells.
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Inventors:
EGUSA, Hiroshi (1-1 Yamadaoka, Suita-sh, Osaka 71, 〒5650871, JP)
江草 宏 (〒71 大阪府吹田市山田丘1番1号 国立大学法人大阪大学内 Osaka, 〒5650871, JP)
YATANI, Hirofumi (1-1 Yamadaoka, Suita-sh, Osaka 71, 〒5650871, JP)
江草 宏 (〒71 大阪府吹田市山田丘1番1号 国立大学法人大阪大学内 Osaka, 〒5650871, JP)
YATANI, Hirofumi (1-1 Yamadaoka, Suita-sh, Osaka 71, 〒5650871, JP)
Application Number:
JP2010/060680
Publication Date:
March 03, 2011
Filing Date:
June 23, 2010
Export Citation:
Assignee:
OSAKA UNIVERSITY (1-1 Yamadaoka, Suita-shi Osaka, 71, 〒5650871, JP)
国立大学法人大阪大学 (〒71 大阪府吹田市山田丘1番1号 Osaka, 〒5650871, JP)
EGUSA, Hiroshi (1-1 Yamadaoka, Suita-sh, Osaka 71, 〒5650871, JP)
江草 宏 (〒71 大阪府吹田市山田丘1番1号 国立大学法人大阪大学内 Osaka, 〒5650871, JP)
国立大学法人大阪大学 (〒71 大阪府吹田市山田丘1番1号 Osaka, 〒5650871, JP)
EGUSA, Hiroshi (1-1 Yamadaoka, Suita-sh, Osaka 71, 〒5650871, JP)
江草 宏 (〒71 大阪府吹田市山田丘1番1号 国立大学法人大阪大学内 Osaka, 〒5650871, JP)
International Classes:
C12N5/10; A61K35/12; A61L27/00; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Saegusa & Partners (Kitahama TNK Building, 1-7-1 Doshomachi, Chuo-ku, Osaka-sh, Osaka 45, 〒5410045, JP)
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