Title:
METHOD FOR EFFICIENTLY PREPARING NICOTINAMIDE MONONUCLEOTIDE AND FUSION PROTEIN
Document Type and Number:
WIPO Patent Application WO/2023/040205
Kind Code:
A1
Abstract:
Provided are a fusion protein and a protein combination thereof, the fusion protein comprising nicotinamide riboside kinase (NRK) and ATP cyclase linked to each other using a linker, and the protein combination comprising the NRK and the ATP cyclase in the fusion protein, a nucleic acid for correspondingly encoding the fusion protein or the protein combination, a recombinant expression vector containing the nucleic acid, a transformant containing the nucleic acid or the recombinant expression vector, and applications thereof. Also provided is a method for preparing nicotinamide mononucleotide using the fusion protein or the protein combination.
Inventors:
SUN HUAJUN (CN)
XIONG SHUTING (CN)
GUO CHEN (CN)
ZHAO WEI (CN)
TAN MIN (CN)
JIANG RUYONG (CN)
ZHENG YAN (CN)
QIAN ZHIQIANG (CN)
XIONG SHUTING (CN)
GUO CHEN (CN)
ZHAO WEI (CN)
TAN MIN (CN)
JIANG RUYONG (CN)
ZHENG YAN (CN)
QIAN ZHIQIANG (CN)
Application Number:
PCT/CN2022/078639
Publication Date:
March 23, 2023
Filing Date:
March 01, 2022
Export Citation:
Assignee:
HUBEI GRAND LIFE SCIENCE AND TECH CO LTD (CN)
International Classes:
C07K19/00; C12N1/19; C12N9/12; C12N15/54; C12N15/62; C12P19/30
Foreign References:
| CN112662699A | 2021-04-16 | |||
| CN112795606A | 2021-05-14 | |||
| US20210246476A1 | 2021-08-12 | |||
| CN105861598A | 2016-08-17 | |||
| CN112608910A | 2021-04-06 | |||
| CN108368493A | 2018-08-03 | |||
| CN112980906A | 2021-06-18 | |||
| CN110373398A | 2019-10-25 | |||
| CN113005162A | 2021-06-22 | |||
| CN112553178A | 2021-03-26 | |||
| CN112437811A | 2021-03-02 |
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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