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Title:
A METHOD FOR ENZYMATIC CROSS-LINKING OF A PROTEIN
Document Type and Number:
WIPO Patent Application WO/2009/153751
Kind Code:
A3
Abstract:
A method for cross-linking albumin for use as a sealant or glue for a biological system, for example to induce hemostasis and/or prevent leakage of any other fluid from a biological tube or tissue, such as lymph for example. The cross-linked albumin may optionally and preferably be applied as part of a bandage for example. In other embodiments, the present invention provides a method of enzymatically cross-linking globular proteins, by altering the structure of the protein to improve the accessibility of the protein to the cross-linking enzyme.

Inventors:
ATTAR ISHAY (IL)
PREISS-BLOOM ORAHN (IL)
Application Number:
PCT/IB2009/052607
Publication Date:
January 20, 2011
Filing Date:
June 18, 2009
Export Citation:
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Assignee:
LIFEBOND LTD (IL)
ATTAR ISHAY (IL)
PREISS-BLOOM ORAHN (IL)
International Classes:
A61L24/10; A61L24/00
Domestic Patent References:
WO2003074004A22003-09-12
Foreign References:
EP0947142A21999-10-06
EP1288264A12003-03-05
US20050209441A12005-09-22
Attorney, Agent or Firm:
Dr. D. GRAESER LTD. et al. (P.O. Box 2496, Raanana, IL)
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