Title:
METHOD FOR THE ENZYMATIC PRODUCTION OF 3-BUTEN-2-ONE
Document Type and Number:
WIPO Patent Application WO/2015/000981
Kind Code:
A3
Abstract:
Described is a method for the production of 3-buten-2-one comprising the enzymatic conversion of 4-hydroxy-2-butanone into 3-buten-2-one by making use of an enzyme catalyzing 4-hydroxy-2-butanone dehydration, wherein said enzyme catalyzing 4-hydroxy-2-butanone dehydration is (a) a 3-hydroxypropiony-CoA dehydratase (EC 4.2.1.116), (b) a 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55), (c) an enoyl-CoA hydratase (EC 4.2.1.17), (d) a 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59), (e) a crotonyl-[acyl-carrier-protein] hydratase (EC 4.2.1.58), (f) a 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60), (g) a 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61 ), (h) a long-chain-enoyl-CoA hydratase (EC 4.2.1.74), or (i) a 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18). The produced 3-buten-2-one can be further converted into 3-buten-2-ol and finally into 1,3-butadiene.
Inventors:
MARLIERE PHILIPPE (BE)
ANISSIMOVA MARIA (FR)
ALLARD MATHIEU (FR)
ANISSIMOVA MARIA (FR)
ALLARD MATHIEU (FR)
Application Number:
PCT/EP2014/064102
Publication Date:
February 19, 2015
Filing Date:
July 02, 2014
Export Citation:
Assignee:
SCIENTIST OF FORTUNE SA (LU)
GLOBAL BIOENERGIES (FR)
GLOBAL BIOENERGIES (FR)
International Classes:
C12P5/02; C12N1/00; C12P7/16; C12P7/26
Domestic Patent References:
| WO2008074794A1 | 2008-06-26 | |||
| WO2013082542A2 | 2013-06-06 | |||
| WO2012174439A2 | 2012-12-20 |
Foreign References:
| US20130109064A1 | 2013-05-02 |
Other References:
ICHIKAWA N ET AL: "Synthesis of 3-buten-2-one from 4-hydroxy-2-butanone over anatase-TiO2 catalyst", CATALYSIS COMMUNICATIONS, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 6, no. 1, 1 January 2005 (2005-01-01), pages 19 - 22, XP027680125, ISSN: 1566-7367, [retrieved on 20050101]
Attorney, Agent or Firm:
VOSSIUS & PARTNER (München, DE)
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