Title:
METHOD OF EXAMINING ALLERGIC DISEASE
Document Type and Number:
WIPO Patent Application WO/2002/052006
Kind Code:
A1
Abstract:
Six genes showing large changes in a plural number of cells are obtained as allergy-associated genes by stimulating airway epithelial cells with IL-4 or IL-13. A method of examining an allergic disease and a method of screening a therapeutically useful compound by using the expression levels of these genes in biological samples as indications are provided.
Inventors:
Ohtani, Noriko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Matsui, Keiko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Yoshida, Nei c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Sugita, Yuji c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Izuhara, Kenji c/o Department of Biochemistry Saga Medical School 5-1-1 (Nabehsima Saga-shi, Saga, 849-8501, JP)
Matsui, Keiko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Yoshida, Nei c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Sugita, Yuji c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Izuhara, Kenji c/o Department of Biochemistry Saga Medical School 5-1-1 (Nabehsima Saga-shi, Saga, 849-8501, JP)
Application Number:
PCT/JP2001/011287
Publication Date:
July 04, 2002
Filing Date:
December 21, 2001
Export Citation:
Assignee:
GENOX RESEARCH, INC. (5-1-3, Tokodai Tsukuba-shi, Ibaraki, 300-2635, JP)
Ohtani, Noriko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Matsui, Keiko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Yoshida, Nei c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Sugita, Yuji c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Izuhara, Kenji c/o Department of Biochemistry Saga Medical School 5-1-1 (Nabehsima Saga-shi, Saga, 849-8501, JP)
Ohtani, Noriko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Matsui, Keiko c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Yoshida, Nei c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Sugita, Yuji c/o Genox Research (Inc. Teikyo University Biotech Center 907 Nogaw, Miyamae-ku Kawasaki-shi Kanagawa, 216-0001, JP)
Izuhara, Kenji c/o Department of Biochemistry Saga Medical School 5-1-1 (Nabehsima Saga-shi, Saga, 849-8501, JP)
International Classes:
A61P37/08; C12N15/12; C12Q1/68; G01N33/50; G01N33/68; (IPC1-7): C12N15/12; C12Q1/68; C12Q1/02; A01K67/027; A61K31/713; A61K45/00; A61K48/00; A61P37/08; G01N33/15; G01N33/50; G01N33/53
Attorney, Agent or Firm:
Shimizu, Hatsushi (Kantetsu Tsukuba Bldg. 6F 1-1-1, Oroshi-machi Tsuchiura-shi, Ibaraki, 300-0847, JP)
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