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Patent Searching and Data


Title:
METHOD OF EXAMINING EFFECT OF ANGIONEGESIS INHIBITOR MEDIATED BY THE INHIBITION OF INTEGRIN EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2002/066073
Kind Code:
A1
Abstract:
A method of examining the effect of a drug on the expression of an integrin which comprises the step of measuring the expression dose of the integrin in platelets of a patients to whom the drug has been administered and the step of evaluating the effect of the drug on the expression of the integrin in cells other than platelets on the basis of the expression dose thus measured.

Inventors:
ONO NAOTO (JP)
SENBA TARO (JP)
HATA NAOKO (JP)
FUNAHASHI YASUHIRO (US)
WAKABAYASHI TOSHIAKI (JP)
Application Number:
PCT/JP2002/001562
Publication Date:
August 29, 2002
Filing Date:
February 21, 2002
Export Citation:
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Assignee:
EISAI C0 LTD (JP)
ONO NAOTO (JP)
SENBA TARO (JP)
HATA NAOKO (JP)
FUNAHASHI YASUHIRO (US)
WAKABAYASHI TOSHIAKI (JP)
International Classes:
A61P9/00; A61P35/00; C07D209/42; C07K14/705; G01N33/50; G01N33/566; (IPC1-7): A61K49/00; A61K31/404; A61K31/506; A61K45/00; A61K31/4439; A61K31/4025; A61P9/00; A61P35/00; C07D209/42; C07D209/30; C07D401/12; C07D403/12; C07D409/12; G01N33/15; G01N33/50; G01N33/49
Domestic Patent References:
WO1999002551A11999-01-21
WO1995007276A11995-03-16
WO2000050395A12000-08-31
WO2001056607A12001-08-09
Other References:
See also references of EP 1362601A4
Attorney, Agent or Firm:
Toyama, Tsutomu (Higashi Nihonbashi 3-chome Chuo-ku, Tokyo, JP)
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