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Title:
METHOD FOR EXAMINING RENAL FUNCTION USING URINAL VEGF-A165B AS AN INDICATOR, EXAMINATION DEVICE, PROGRAM FOR FUNCTIONING AS RENAL FUNCTION EXAMINATION DEVICE, AND RECORDING MEDIUM
Document Type and Number:
WIPO Patent Application WO/2016/194708
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an examination method whereby a decrease in renal function can be examined even in an early stage thereof. The above problem is solved by a renal function examination method wherein the content of VEGF-A165b in urine is measured, and the measured content is used as an indicator.

Inventors:
KIKUCHI RYOSUKE (JP)
MATSUSHITA TADASHI (JP)
MUROHARA TOYOAKI (JP)
Application Number:
PCT/JP2016/065325
Publication Date:
December 08, 2016
Filing Date:
May 24, 2016
Export Citation:
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Assignee:
NAT UNIV CORP NAGOYA UNIV (JP)
International Classes:
G01N33/68; G01N33/48
Foreign References:
JP2012509306A2012-04-19
JP2014193920A2014-10-09
JP2011504092A2011-02-03
Other References:
GRENDA, RYSZARD ET AL.: "Urinary excretion of endothelin-1 (ET-1), transforming growth factor-beta1 (TGF-beta1) and vascular endothelial growth factor (VEGF165) in paediatric chronic kidney diseases: results of the ESCAPE trial", NEPHROL DIAL TRANSPLANT, vol. 22, 2007, pages 3487 - 3494, XP055332995
HONKANEN, O. EERO ET AL.: "Decreased urinary excretion of vascular endothelial growth factor in idiopathic membranous glomerulonephritis", KIDNEY INTERNATIONAL, vol. 57, 2000, pages 2343 - 2349, XP055332997
AVIHINGSANON, YINGYOS ET AL.: "Decreased renal expression of vascular endothelial growth factor in lupus nephritis is associated with worse prognosis", KIDNEY INTERNATIONAL, vol. 75, 2009, pages 1340 - 1348, XP055332999
Attorney, Agent or Firm:
MATSUMOTO SEIJI (JP)
Seiji Matsumoto (JP)
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