Title:
METHOD FOR EXTRACTING CITRULLINE FROM WATERMELON
Document Type and Number:
WIPO Patent Application WO/2020/042557
Kind Code:
A1
Abstract:
The present invention relates to the technical field of natural substance extraction. Disclosed is a method for extracting citrulline from a watermelon. The method for extracting citrulline from a watermelon in the present invention comprises raw material pre-treatment, ultrasound-enzymatic hydrolysis assisted solvent leaching, and purification steps. The purification step comprises microbial fermentation, ion-exchange resin purification, macroporous adsorption resin discoloration, and crystallization and recrystallization. The method for extracting citrulline in the present invention is simple, requires a mild condition, and has a good extraction effect on citrulline. The purity of citrulline after purification is more than 90%. In addition, the citrulline extracted by the method in the present invention meets the related health requirements and product quality standards, can be applied to food and health food industries as a raw material, and has natural security advantages.
Inventors:
JIAO ZHONGGAO (CN)
LIU JIECHAO (CN)
ZHANG CHUNLING (CN)
ZHANG QIANG (CN)
LIU HUI (CN)
LV ZHENZHEN (CN)
YANG WENBO (CN)
CHEN DALEI (CN)
LIU JIECHAO (CN)
ZHANG CHUNLING (CN)
ZHANG QIANG (CN)
LIU HUI (CN)
LV ZHENZHEN (CN)
YANG WENBO (CN)
CHEN DALEI (CN)
Application Number:
PCT/CN2019/076459
Publication Date:
March 05, 2020
Filing Date:
February 28, 2019
Export Citation:
Assignee:
ZHENGZHOU FRUIT RES INST CAACULTURAL SCIENCES (CN)
International Classes:
C07C273/18; C07C275/16
Foreign References:
| CN108822001A | 2018-11-16 | |||
| CN101880245A | 2010-11-10 | |||
| CN103360283A | 2013-10-23 | |||
| CN105400851A | 2016-03-16 | |||
| US8173837B1 | 2012-05-08 | |||
| CN101372465A | 2009-02-25 |
Attorney, Agent or Firm:
BEIJING TIAN QI ZHI XIN INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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