Title:
METHOD FOR EXTRACTING GRIFOLA FRONDOSA ACTIVE POLYSACCHARIDE, AND EXTRACTED ACTIVE POLYSACCHARIDE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/077853
Kind Code:
A1
Abstract:
The present invention relates to a method for extracting grifola frondosa active polysaccharide on the basis of a membrane filtration technology, and grifola frondosa active polysaccharide extracted by the method and a use thereof. The method comprises: (1) adding water to a grifola frondosa sporocarp raw material, and performing combination and vacuum concentration to obtain a grifola frondosa extract concentrate; (2) performing microfiltration pretreatment on the grifola frondosa extract concentrate; (3) performing ultrafiltration treatment on the microfiltration permeate; and (4) drying the ultrafiltration retentate to obtain grifola frondosa polysaccharide. The present invention has beneficial effects that: (1) active components in the grifola frondosa extract are prevented from being damaged to the maximum extent, and a separation process is equivalent to primary pre-concentration; the ultrafiltration technology in the present invention is very suitable for separating effective components in the extract and removing components which are poor and even invalid in efficacy; the purity of the prepared grifola frondosa polysaccharide is higher than that of polysaccharide prepared by means of a conventional process; the ultrafiltration effect is improved, the membrane pollution is reduced, the production efficiency is improved, the service life of the ultrafiltration membrane is prolonged, and the costs are reduced; and the present invention is suitable for industrialization and has good economic prospects.
Inventors:
JIAO CHUNWEI (CN)
XIE YIZHEN (CN)
LI SHUNXIAN (CN)
HE CHUNYAN (CN)
MA XIAOWEI (CN)
CHEN JIAMING (CN)
LI JIEYI (CN)
XIE YIZHEN (CN)
LI SHUNXIAN (CN)
HE CHUNYAN (CN)
MA XIAOWEI (CN)
CHEN JIAMING (CN)
LI JIEYI (CN)
Application Number:
PCT/CN2021/080132
Publication Date:
April 21, 2022
Filing Date:
March 11, 2021
Export Citation:
Assignee:
GUANGDONG YUEWEI BIOSCIENCE CO LTD (CN)
International Classes:
C08B37/00; A61P3/10
Foreign References:
| CN112225827A | 2021-01-15 | |||
| CN104262501A | 2015-01-07 | |||
| CN103724445A | 2014-04-16 | |||
| CN102408494A | 2012-04-11 | |||
| CN105732250A | 2016-07-06 | |||
| CN101736053A | 2010-06-16 | |||
| JP5882635B2 | 2016-03-09 |
Attorney, Agent or Firm:
HON.BAN PATENT & TRADEMARK FIRM (CN)
Download PDF: