Title:
METHOD AND FORMULATION FOR TREATING ADVERSE BIOLOGICAL CONDITIONS
Document Type and Number:
WIPO Patent Application WO/2010/019276
Kind Code:
A3
Abstract:
A method for treatment of adverse biological conditions is provided, wherein a biologically active agent such as a macromolecular biomolecule, e.g., a nucleic acid or a peptidic compound, is administered to a subject in need of such treatment in a formulation containing a transport enhancer having the structure of formula (I) wherein Q, R1, and R2 are as defined herein. Methylsulfonylmethane (MSM) is a representative and preferred transport enhancer. Formulations are also provided.
Inventors:
BHUSHAN RAJIV (US)
GIN JERRY B (US)
GOSWAMY AMIT (US)
GIN JERRY B (US)
GOSWAMY AMIT (US)
Application Number:
PCT/US2009/004709
Publication Date:
June 03, 2010
Filing Date:
August 17, 2009
Export Citation:
Assignee:
LIVIONEX INC (US)
BHUSHAN RAJIV (US)
GIN JERRY B (US)
GOSWAMY AMIT (US)
BHUSHAN RAJIV (US)
GIN JERRY B (US)
GOSWAMY AMIT (US)
International Classes:
A61K31/10; A61K31/7105; A61K38/19; A61K39/395; A61K48/00; A61P3/10; A61P35/00
Domestic Patent References:
| WO2004002534A1 | 2004-01-08 | |||
| WO2007149287A2 | 2007-12-27 |
Foreign References:
| US20060177430A1 | 2006-08-10 | |||
| US6403116B1 | 2002-06-11 | |||
| EP1254961A1 | 2002-11-06 |
Other References:
See also references of EP 2328570A4
Attorney, Agent or Firm:
BASU, Shantanu et al. (2225 East Bayshore RoadSuite 200,Palo Alto, CA, US)
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