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Title:
METHOD FOR GRAFTING SURFACE OF MEDICAL DEVICE BY USING QUATERNIZED TRIMETHYLAMINE
Document Type and Number:
WIPO Patent Application WO/2022/191637
Kind Code:
A1
Abstract:
The present invention relates to a method for grafting a surface of a medical device by using quaternized trimethylamine. A catheter onto which quaternized trimethylamine has been grafted allows for the reduction of thrombus production. Therefore, the catheter having quaternized trimethylamine grafted thereto exhibits the effect of repressing thrombus production and enhancing the function of inhibiting blood adsorption and blood cell adsorption.

Inventors:
KIM DO YEON (KR)
KANG JONG HEE (KR)
HAN SU GYUNG (KR)
Application Number:
PCT/KR2022/003363
Publication Date:
September 15, 2022
Filing Date:
March 10, 2022
Export Citation:
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Assignee:
VASULAR INTERFACE INC (KR)
International Classes:
A61L33/00; A61L29/08; A61M25/00
Foreign References:
JP2015509114A2015-03-26
JP6753041B22020-09-09
KR101720423B12017-03-27
Other References:
TU QIN, WANG JIAN-CHUN, LIU RUI, HE JUAN, ZHANG YANRONG, SHEN SHAOFEI, XU JUAN, LIU JIANJUN, YUAN MAO-SEN, WANG JINYI: "Antifouling properties of poly(dimethylsiloxane) surfaces modified with quaternized poly(dimethylaminoethyl methacrylate)", COLLOIDS AND SURFACES B: BIOINTERFACES, ELSEVIER AMSTERDAM, NL, vol. 102, 1 February 2013 (2013-02-01), NL , pages 361 - 370, XP055966443, ISSN: 0927-7765, DOI: 10.1016/j.colsurfb.2012.08.033
XU LI QUN, LI NING NING, CHEN JIU CUN, FU GUO DONG, KANG EN-TANG: "Quaternized poly(2-(dimethylamino)ethyl methacrylate)-grafted agarose copolymers for multipurpose antibacterial applications", RSC ADVANCES, vol. 5, no. 76, 1 January 2015 (2015-01-01), pages 61742 - 61751, XP055966445, DOI: 10.1039/C5RA11189G
Attorney, Agent or Firm:
ECM IP & LAW FIRM (KR)
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