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Title:
METHOD FOR IDENTIFYING CELLS
Document Type and Number:
WIPO Patent Application WO/2014/112655
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for analyzing the epigenetic state of stem cells in detail. Provided is a method for identifying stem cells, said method being characterized by comprising analyzing the methylation and demethylation patterns of chromosome DNA that is extracted from stem cells to be inspected, and then relating the patterns thus analyzed to the characteristics of the stem cells to be inspected.

Inventors:
TAJIMA HIDEJI (JP)
GINYA HARUMI (JP)
HATANO TOMOYUKI (JP)
TAKAHASHI MASAAKI (JP)
KARINAGA RYOUJI (JP)
Application Number:
PCT/JP2014/051316
Publication Date:
July 24, 2014
Filing Date:
January 16, 2014
Export Citation:
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Assignee:
UNIVERSAL BIO RESEARCH CO LTD (JP)
International Classes:
C12Q1/68; G01N33/48; G01N33/53; G01N37/00; G16B25/10; C12N5/0735; C12N5/074; C12N5/0775
Domestic Patent References:
WO2012037456A12012-03-22
WO2012141324A12012-10-18
Foreign References:
JP2006524033A2006-10-26
JP2009165478A2009-07-30
Other References:
NATURE BIOTECHNOLOGY, vol. 25, no. 7, 2007, pages 803 - 816
JAMES R. TOLLERVEY ET AL., EPIGENETICS, vol. 7, 2012, pages 823 - 840
KOICHIRO NISHINO ET AL., PLOS ONE, vol. 5, 2010, pages E13017
JULIA ARAND ET AL., PLOS ONE, vol. 8, 2012, pages EL002750
COLM NESTOR ET AL., BIOTECHNIQUE, vol. 48, 2010, pages 317 - 319
YUN HUANG ET AL., PLOS ONE, vol. 5, 2010, pages E8888
LI N ET AL., METHODS, vol. 52, 2010, pages 203 - 212
JOSHUA D. TOMPKINS ET AL., PNAS, vol. 109, 2012, pages 12544 - 12549
STRELCHENKO N ET AL., REPROD BIOMED ONLINE, vol. 9, 2004, pages 623 - 629
KLIMANSKAYA I ET AL., NATURE, vol. 444, 2006, pages 481 - 485
CHUNG Y ET AL., CELL STEM CELL, vol. 2, 2008, pages 113 - 117
RIKEN CDB, HUMAN STEM CELL RESEARCH SUPPORT OFFICE PROTOCOLS, 2008
TAKAHASHI, K. ET AL., CELL, vol. 131, 30 November 2007 (2007-11-30), pages 861 - 872
THOMSON, J.A. ET AL., SCIENCE, vol. 282, 6 November 1998 (1998-11-06), pages 1145 - 1147
TAKAHASHI K ET AL., CELL, vol. 126, 2006, pages 663 - 676
TAKAHASHI K ET AL., CELL, vol. 131, 2007, pages 861 - 872
SCACHERI ET AL., METHODS ENZYMOL, vol. 411, 2006, pages 270 - 82
RAKYAN VK ET AL., GENOME RES, vol. 18, 2008, pages 1518 - 1529
NICOL JW ET AL., BIOINFORMATICS, 4 August 2009 (2009-08-04)
HELT GA ET AL., BMC BIOINFORMATICS, vol. 10, no. 1, 25 August 2009 (2009-08-25), pages 266
See also references of EP 2947157A4
Attorney, Agent or Firm:
KOBAYASHI, Hiroshi et al. (JP)
Kobayashi 浩 (JP)
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