Title:
METHOD FOR IDENTIFYING EXOSOME SURFACE MOLECULE
Document Type and Number:
WIPO Patent Application WO/2019/044845
Kind Code:
A1
Abstract:
The present invention provides a method for identifying an exosome surface molecule, characterized by comprising: blocking and cleaning, with a casein solution or a casein digest solution, a carrier in which a molecule bindable to an exosome surface molecule is formed into a solid phase; and mixing the casein solution or the casein digest solution with an exosome-containing test sample prior to bringing said carrier into contact with the test sample.
Inventors:
IRIKURA DAISUKE (JP)
NAKAYAMA HIDEKI (JP)
NAKAYAMA HIDEKI (JP)
Application Number:
PCT/JP2018/031798
Publication Date:
March 07, 2019
Filing Date:
August 28, 2018
Export Citation:
Assignee:
HORIBA LTD (JP)
International Classes:
G01N33/53; C12M1/00; G01N21/41; G01N33/543; C07K14/42; C07K14/705; C07K16/00; C12N15/115
Domestic Patent References:
WO2016147825A1 | 2016-09-22 | |||
WO2015129361A1 | 2015-09-03 | |||
WO2017104616A1 | 2017-06-22 |
Foreign References:
JP2015230280A | 2015-12-21 |
Other References:
IM, H. ET AL.: "Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor", NATURE BIOTECHNOLOGY, vol. 32, no. 5, 20 April 2014 (2014-04-20), pages 490 - 495, XP055207677, Retrieved from the Internet DOI: doi:10.1038/nbt.2886
GRASSO, L. ET AL.: "Molecular screening of cancer-derived exosomes by surface plasmon resonance spectroscopy", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 407, no. 18, 30 April 2015 (2015-04-30), pages 5425 - 5432, XP055580880, DOI: 10.1007/s00216-015-8711-5
GRASSO, L. ET AL.: "Molecular screening of cancer-derived exosomes by surface plasmon resonance spectroscopy", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 407, no. 18, 30 April 2015 (2015-04-30), pages 5425 - 5432, XP055580880, DOI: 10.1007/s00216-015-8711-5
Attorney, Agent or Firm:
TAKASHIMA, Hajime et al. (JP)
Download PDF:
Previous Patent: NOVEL Sin3 MODULATOR AND MEDICAL APPLICATION THEREOF
Next Patent: MOLDED ARTICLE EXTRACTING DEVICE
Next Patent: MOLDED ARTICLE EXTRACTING DEVICE