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Title:
METHOD FOR INCREASING RESISTANCE AGAINST STRESS FACTORS IN PLANTS
Document Type and Number:
WIPO Patent Application WO2004081217
Kind Code:
A3
Abstract:
The invention relates to a method for producing or increasing resistance against at least one biotic or abiotic stress factor in plants, preferably against plant pathogens, by increasing expression of at least one Bax inhibitor 1 (BI1) protein in at least one plant tissue, under the proviso that expression in leaf epidermis remains substantially unmodified. The invention relates further to recombinant expression cassettes and vectors that comprise a nucleic acid sequence coding for the BI protein under the control of a tissue-specific promoter, said promoter having substantially no activity in leaf epidermis. The invention further relates to recombinant plants that are transformed with said expression cassettes or vectors, to cultures, parts or recombinant propagation material derived thereof, and to the use of the same for producing food, feeding stuff, seeds, pharmaceuticals or fine chemicals.

Inventors:
FRANK MARKUS (DE)
KOGEL KARL-HEINZ (DE)
HUECKELHOVEN RALPH (DE)
Application Number:
PCT/EP2004/002436
Publication Date:
December 23, 2004
Filing Date:
March 10, 2004
Export Citation:
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Assignee:
BASF PLANT SCIENCE GMBH (DE)
FRANK MARKUS (DE)
KOGEL KARL-HEINZ (DE)
HUECKELHOVEN RALPH (DE)
International Classes:
C07K14/415; C12N15/29; C12N15/82; (IPC1-7): C12N15/82; C07K14/415; C12N15/29; A01H5/00
Domestic Patent References:
WO2002101079A22002-12-19
WO2000026391A22000-05-11
Foreign References:
US20030009785A12003-01-09
EP0864650A21998-09-16
Other References:
LINCOLN JAMES E ET AL: "Expression of the antiapoptotic baculovirus p35 gene in tomato blocks programmed cell death and provides broad-spectrum resistance to disease.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 99, no. 23, 12 November 2002 (2002-11-12), November 12, 2002, pages 15217 - 15221, XP002286824, ISSN: 0027-8424 (ISSN print)
HUECKELHOVEN RALPH ET AL: "Overexpression of barley BAX inhibitor 1 induces breakdown of mlo-mediated penetration resistance to Blumeria graminis.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 100, no. 9, 29 April 2003 (2003-04-29), April 29, 2003, pages 5555 - 5560, XP002286823, ISSN: 0027-8424 (ISSN print)
CHAE H-J ET AL: "Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 323, 24 December 2003 (2003-12-24), pages 101 - 113, XP004477034, ISSN: 0378-1119
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