Title:
METHOD FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS IN VITRO
Document Type and Number:
WIPO Patent Application WO/2018/025975
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a cell creation method that enables a reduction in cost and time, that is highly safe, and that has great potential for being industrially applied. Provided by the present invention is a method for inducing differentiation of pluripotent cells in vitro into cells having a same phenotype and function as information-presentation cells, the method comprising co-culturing pluripotent cells or a cellular fraction having said pluripotent cells concentrated therein, together with damaged cells or dead cells derived from information-presentation cells, or together with a portion of the damaged cells or dead cells derived from information-presentation cells.
Inventors:
DEZAWA MARI (JP)
Application Number:
PCT/JP2017/028327
Publication Date:
February 08, 2018
Filing Date:
August 03, 2017
Export Citation:
Assignee:
LIFE SCIENCE INST INC (JP)
International Classes:
C12N5/071; C12N5/074; C12Q1/04; C12N15/09
Domestic Patent References:
| WO2011007900A1 | 2011-01-20 |
Foreign References:
| JP2010268789A | 2010-12-02 |
Other References:
HOI WAN TSO G. ET AL.: "Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL - 17 and RANKL expression on CD 4+ T cells", STEM CELLS, vol. 28, 2010, pages 939 - 954, XP055460275, DOI: doi:10.1002/stem.406
See also references of EP 3495471A4
See also references of EP 3495471A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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