Title:
METHOD FOR ISOLATING AND CULTURING TARGET CELLS USING BIOCOMPATIBLE POLYMERIC NANOFIBER SCAFFOLD TO WHICH TARGET-SPECIFIC LIGAND BINDS
Document Type and Number:
WIPO Patent Application WO/2013/168979
Kind Code:
A1
Abstract:
The present invention provides a method for isolating and culturing target cells using a biocompatible polymeric nanofiber scaffold to which a target-specific ligand binds. According to the invention, the use of the biocompatible polymeric nanofiber scaffold to which the target-specific ligand binds enables the target cells to be isolated rapidly and simply, as well as specifically and efficiently. Thus, the present invention can be effectively used in the development of a method for isolating a specific desired cell from a sample in which a variety of cells are mixed, and in a cell-isolating device.
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Inventors:
LEE KYUNG MI (KR)
KIM KWANG HEE (KR)
SHIN HEUNG SOO (KR)
KIM TAE HOON (KR)
YEE CASSIAN (KR)
KIM KWANG HEE (KR)
SHIN HEUNG SOO (KR)
KIM TAE HOON (KR)
YEE CASSIAN (KR)
Application Number:
PCT/KR2013/003982
Publication Date:
November 14, 2013
Filing Date:
May 07, 2013
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
IUCF HYU (KR)
IUCF HYU (KR)
International Classes:
G01N33/53; C12Q1/24; G01N33/50
Foreign References:
| KR20110094475A | 2011-08-24 |
Other References:
KIM, YOUNG JIN ET AL.: "3-D Rat Hepatocytes' Culture on Polystyrene Nanofibrous Scaffold", POLYMER, vol. 32, no. 2, 2008, KOREA, pages 131 - 137
CHUA ET AL.: "Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold", BIOMATERIALS, vol. 26, no. 15, 2005, pages 2537 - 2547
CHUA ET AL.: "Surface-aminated electro spun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells", BIOMATERIALS, vol. 27, no. 36, 2006, pages 6043 - 6051
NOH, YOUNG WOOCK ET AL.: "Immunocyte Bioimaging for Treatment using Polymer Nanoparticles", POLYMER SCIENCE AND TECHNOLOGY, vol. 20, no. 3, June 2009 (2009-06-01), pages 226 - 231
CHUA ET AL.: "Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold", BIOMATERIALS, vol. 26, no. 15, 2005, pages 2537 - 2547
CHUA ET AL.: "Surface-aminated electro spun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells", BIOMATERIALS, vol. 27, no. 36, 2006, pages 6043 - 6051
NOH, YOUNG WOOCK ET AL.: "Immunocyte Bioimaging for Treatment using Polymer Nanoparticles", POLYMER SCIENCE AND TECHNOLOGY, vol. 20, no. 3, June 2009 (2009-06-01), pages 226 - 231
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
특허법인 다나 (KR)
특허법인 다나 (KR)
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