Title:
METHOD FOR ISOLATING ISLET OF NEWBORN PIG
Document Type and Number:
WIPO Patent Application WO/2018/105805
Kind Code:
A1
Abstract:
The present invention relates to a method for isolating an islet from a newborn pig and, specifically, to a method for isolating an islet of a newborn pig, the method comprising the steps of: (a) extracting an islet from a newborn pig; (b) injecting an enzyme into an extracted pancreas; and (c) inducing the activation of the enzyme. The use of the method for isolating an islet according to the present invention can isolate a high-quality islet from a newborn pig at high efficiency, and thus can lead to not only the utilization as an islet isolation technique for xenotransplantation but also the development of techniques for isolation, culture, and quality analysis of an islet of a newborn pig, and therefore, the method according to the present invention can be widely utilized in the biomedical field, such as diabetes treatment.
Inventors:
AHN CURIE (KR)
LEE EUN MI (KR)
ZAHID ALAM MD (KR)
LEE EUN MI (KR)
ZAHID ALAM MD (KR)
Application Number:
PCT/KR2017/000273
Publication Date:
June 14, 2018
Filing Date:
January 09, 2017
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
International Classes:
C12N5/071
Domestic Patent References:
| WO1997039107A2 | 1997-10-23 |
Foreign References:
| KR100686383B1 | 2007-02-22 | |||
| KR20130091260A | 2013-08-16 | |||
| KR20070095956A | 2007-10-01 |
Other References:
PARK, SOL JI ET AL.: "Functional Improvement of Porcine Neonatal Pancreatic Cell Clusters via Conformal Encapsulation Using an Air-driven Encapsulator", EXPERIMENTAL AND MOLECULAR MEDICINE, vol. 44, no. 1, January 2012 (2012-01-01), pages 20 - 25, XP055510111
Attorney, Agent or Firm:
CHO, Young Hyun (KR)
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