Title:
METHOD AND KIT FOR ENHANCING THE ASSOCIATION RATES OF POLYNUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO2002048404
Kind Code:
A3
Abstract:
The present invention features a method and associated kit for increasing the association rate between polynucleotides having complementary, single-stranded regions, where the method includes providing to a test sample containing the complementary polynucleotides one or more synthetic, water soluble polycationic polymers.
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Inventors:
BECKER MICHAEL M
Application Number:
PCT/US2001/048592
Publication Date:
October 23, 2003
Filing Date:
December 07, 2001
Export Citation:
Assignee:
GEN PROBE INC (US)
International Classes:
C12N15/09; C12Q1/68; G01N33/53; C12Q1/6818; C12Q1/6832; C12Q1/6839; C12Q1/70; G01N33/566; (IPC1-7): C12Q1/68; C12Q1/70
Domestic Patent References:
| WO1997043450A1 | 1997-11-20 | |||
| WO2000072016A1 | 2000-11-30 | |||
| WO1995006056A1 | 1995-03-02 |
Foreign References:
| US5747254A | 1998-05-05 | |||
| US4834854A | 1989-05-30 | |||
| US6017700A | 2000-01-25 |
Other References:
TYAGI S ET AL: "MOLECULAR BEACONS: PROBES THAT FLUORESCE UPON HYBRIDIZATION", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 14, March 1996 (1996-03-01), pages 303 - 308, XP002926498, ISSN: 0733-222X
MARUYAMA ATSUSHI ET AL: "Characterization of interpolyelectrolyte complexes between double-stranded DNA and polylysine comb-type copolymers having hydrophilic side chains.", BIOCONJUGATE CHEMISTRY, vol. 9, no. 2, March 1998 (1998-03-01), pages 292 - 299, XP002249706, ISSN: 1043-1802
MAJLESSI MEHRDAD ET AL: "Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets.", NUCLEIC ACIDS RESEARCH, vol. 26, no. 9, 1 May 1998 (1998-05-01), pages 2224 - 2229, XP002249707, ISSN: 0305-1048
DATABASE WPI Section Ch Week 200332, Derwent World Patents Index; Class B04, AN 2003-342454, XP002249761
MARUYAMA ATSUSHI ET AL: "Characterization of interpolyelectrolyte complexes between double-stranded DNA and polylysine comb-type copolymers having hydrophilic side chains.", BIOCONJUGATE CHEMISTRY, vol. 9, no. 2, March 1998 (1998-03-01), pages 292 - 299, XP002249706, ISSN: 1043-1802
MAJLESSI MEHRDAD ET AL: "Advantages of 2'-O-methyl oligoribonucleotide probes for detecting RNA targets.", NUCLEIC ACIDS RESEARCH, vol. 26, no. 9, 1 May 1998 (1998-05-01), pages 2224 - 2229, XP002249707, ISSN: 0305-1048
DATABASE WPI Section Ch Week 200332, Derwent World Patents Index; Class B04, AN 2003-342454, XP002249761
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