Title:
A METHOD OF LYOPHYLIZATION TO REDUCE SOLVENT CONTENT AND ENHANCE PRODUCT RECOVERY
Document Type and Number:
WIPO Patent Application WO2003026786
Kind Code:
A3
Abstract:
The present invention relates to an improved method for lyophilization or freeze-drying. More specifically, the present invention relates to methods for reducing the residual solvent content of a material during lyophilization or freeze-drying by the addition of a compound effective therefor, such as ascorbic acid, or a suitable derivative thereof, such as a salt or ester thereof, or mannitol.
Inventors:
BURGESS WILSON H (US)
DROHAN WILLIAM N (US)
MACPHEE MARTIN J (US)
MANN DAVID M (US)
BEALL DAWSON (US)
DROHAN WILLIAM N (US)
MACPHEE MARTIN J (US)
MANN DAVID M (US)
BEALL DAWSON (US)
Application Number:
PCT/US2002/028138
Publication Date:
October 16, 2003
Filing Date:
September 24, 2002
Export Citation:
Assignee:
CLEARANT INC (US)
BURGESS WILSON H (US)
DROHAN WILLIAM N (US)
MACPHEE MARTIN J (US)
MANN DAVID M (US)
BEALL DAWSON (US)
BURGESS WILSON H (US)
DROHAN WILLIAM N (US)
MACPHEE MARTIN J (US)
MANN DAVID M (US)
BEALL DAWSON (US)
International Classes:
A01N1/02; F26B5/00; F26B5/06; (IPC1-7): A61K31/047; A61K31/19
Domestic Patent References:
| WO1997017435A1 | 1997-05-15 |
Foreign References:
| EP0308238A1 | 1989-03-22 |
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