Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
THE METHOD FOR MAKING CANDIXATAN ESTER AND INTERMEDIATES THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/131582
Kind Code:
A1
Abstract:
The method for making candixatan ester and intermediates thereof and a compound of formula III, wherein R1 is triphenylmethyl, methxoycarbonyl, ethoxycarbonyl, tert-butoxycarbonyl, benzoxycarbonyl, trimethylsilane, triethylsliane or tritertbutylsilane protect group, and R2 is triphenylmethyl, methxoycarbonyl, ethoxycarbonyl, tert-butoxycarbonyl, benzoxycarbonyl, trimethylsilane, triethylsliane or tritertbutylsilane protect group. The method for making candixatan ester by the said compound of formula III is also provided. The invention is a completely new synthesis route of candixatan ester which is shorter than ever, and the raw material is easily obtained, and the operation is simple. The new synthesis route of candixatan ester of the invention shortens the reaction route and simplifies the operation procedure. Furthermore, the new synthesis route of candixatan ester of the invention avoids the use of organo-tin and nitrine compounds, and which is safety and protects the environment.

Inventors:
LI HAIHONG (CN)
YANG CHI (CN)
LIU ZHENG (CN)
LI JIANFENG (CN)
SHEN JINGSHAN (CN)
Application Number:
PCT/CN2007/001392
Publication Date:
November 06, 2008
Filing Date:
April 26, 2007
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
TOPHARMAN SHANGHAI CO LTD (CN)
LI HAIHONG (CN)
YANG CHI (CN)
LIU ZHENG (CN)
LI JIANFENG (CN)
SHEN JINGSHAN (CN)
International Classes:
C07D257/04; C07D403/10
Foreign References:
CN1800179A2006-07-12
CN1361101A2002-07-31
Attorney, Agent or Firm:
BEIJING HUIZE INTELLECTUAL PROPERTY LAW LLC (Horizon International TowerNo. 6 Zhichun Road,Haidian District, Beijing 8, CN)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: SYSTEM AND METHOD FOR UPDATING UATI OF AN ACCESS TERMINAL

Next Patent: SEALED CONTAINER OF VACUUM-PUMPING