Title:
METHOD FOR MANUFACTURING MICROORGANISM-DERIVED EXTRACELLULAR VESICLES HAVING IMPROVED YIELD, AND COMPOSITION FOR IMPROVING SKIN CONDITION COMPRISING EXTRACELLULAR VESICLES MANUFACTURED THEREBY
Document Type and Number:
WIPO Patent Application WO/2022/055250
Kind Code:
A1
Abstract:
The present invention relates to a method for manufacturing microorganism-derived extracellular vesicles having improved yield by means of cell lysis, and to a composition for improving a skin condition comprising lactic acid bacteria-derived extracellular vesicles manufactured by the method. The method for manufacturing microorganism-derived extracellular vesicles, according to one aspect, can obtain, in large quantities, extracellular vesicles having excellent functional activities such as anti-inflammatory and skin whitening activities, and thus can be useful in the manufacture of a composition for improving skin conditions.
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Inventors:
KANG YONG WON (KR)
PARK OH SEONG (KR)
WANG HYE SOO (KR)
LEE KWANG SOO (KR)
PARK OH SEONG (KR)
WANG HYE SOO (KR)
LEE KWANG SOO (KR)
Application Number:
PCT/KR2021/012219
Publication Date:
March 17, 2022
Filing Date:
September 08, 2021
Export Citation:
Assignee:
BIOSOLUTION CO LTD (KR)
International Classes:
C12N1/20; A23L33/135; A61K8/99; A61Q19/00; B01D61/14
Domestic Patent References:
| WO2019178055A1 | 2019-09-19 |
Foreign References:
| KR20190002079A | 2019-01-08 | |||
| KR20080092090A | 2008-10-15 | |||
| KR20160110232A | 2016-09-21 |
Other References:
KIM WANIL, LEE EUN JUNG, BAE IL‐HONG, MYOUNG KILSUN, KIM SUNG TAE, PARK PHIL JUNE, LEE KYUNG‐HA, PHAM AN VUONG QUYNH, KO JAEYOUNG,: "Lactobacillus plantarum ‐derived extracellular vesicles induce anti‐inflammatory M2 macrophage polarization in vitro", JOURNAL OF EXTRACELLULAR VESICLES, TAYLOR & FRANCIS, UK, vol. 9, no. 1793514, 17 July 2020 (2020-07-17), UK , pages 1 - 15, XP055857535, ISSN: 2001-3078, DOI: 10.1080/20013078.2020.1793514
WANG HYESOO, LEE KWANG-SOO, KANG YONG-WON: "Skin Barrier Improvement Effect of Exosomal Nanovesicles Derived from Lactic Acid Bacteria", JOURNAL OF THE SOCIETY OF COSMETIC SCIENTISTS OF KOREA, SOCIETY OF COSMETIC SCIENTISTS OF KOREA, KOREA, vol. 47, no. 2, 30 June 2021 (2021-06-30), Korea , pages 171 - 178, XP055911018, ISSN: 1226-2587, DOI: 10.15230/SCSK.2021.47.2.171
WANG HYESOO, LEE KWANG-SOO, KANG YONG-WON: "Skin Barrier Improvement Effect of Exosomal Nanovesicles Derived from Lactic Acid Bacteria", JOURNAL OF THE SOCIETY OF COSMETIC SCIENTISTS OF KOREA, SOCIETY OF COSMETIC SCIENTISTS OF KOREA, KOREA, vol. 47, no. 2, 30 June 2021 (2021-06-30), Korea , pages 171 - 178, XP055911018, ISSN: 1226-2587, DOI: 10.15230/SCSK.2021.47.2.171
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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