Title:
METHOD FOR MANUFACTURING NITROBENZENE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2014/208296
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an economically favorable, industrialization-suitable method for manufacturing nitrobenzene compounds of general formula (1). A method for manufacturing nitrobenzene compounds of general formula (1): (in the formula, R1 represents a halogen atom; R2, R3 and R4 represent a hydrogen atom, etc.; and R5 represents a halogen atom or alkoxycarbonyl group), the method comprising the following processes: (i) a process for reacting aniline compounds of general formula (2): (in the formula, R1, R2, R3, R4 and R5 are as previously defined.) in the presence of a metal salt of nitrous acid and an acid, and (ii) a process for reacting the product of process (i) in the presence of a metal salt of nitrous acid and a copper compound; and the total amount of water used in process (ii) being 1.2-2.2 L (liters) with respect to one mole of the compound of general formula (2).
Inventors:
IKUMI AKIKO (JP)
NAKAMURA TAKAYUKI (JP)
NAKAMURA TAKAYUKI (JP)
Application Number:
PCT/JP2014/064780
Publication Date:
December 31, 2014
Filing Date:
June 03, 2014
Export Citation:
Assignee:
IHARA CHEMICAL IND CO (JP)
International Classes:
C07C201/06; C07C205/12; C07C205/58; C07B61/00
Domestic Patent References:
| WO2005081960A2 | 2005-09-09 | |||
| WO2013005425A1 | 2013-01-10 |
Foreign References:
| JP2606291B2 | 1997-04-30 | |||
| JP2005533756A | 2005-11-10 | |||
| JP2008537953A | 2008-10-02 | |||
| US5084086A | 1992-01-28 | |||
| JP2606291B2 | 1997-04-30 |
Other References:
FENG RONG-XIU ET AL.: "Synthesis of 3-Chloro-2- Nitrotoluene", TRANSACTIONS OF TIANJIN UNIVERSITY, vol. 8, no. 1, March 2002 (2002-03-01), pages 40 - 42, XP008182596
TRANSACTIONS OF T IANJ IN UNIVERSITY, vol. 8, no. 1, 2002, pages 40 - 41
"Shin-Jikkenkagaku Koza 9, Bunseki Kagaku II", 1977, MARUZENCOMPANY, LIMITED, pages: 86 - 112
"Jikkenkagaku Koza 20-1, Bunseki Kagaku", 2007, MARUZEN COMPANY, LIMITED, pages: 130 - 151
"Shin-Jikkenkagaku Koza 9, Bunseki Kagaku II", 1977, MARUZEN COMPANY, LIMITED, pages: 60 - 86
"Jikkenkagaku Koza 20-1, Bunseki Kagaku", 2007, MARUZEN COMPANY, LIMITED, pages: 121 - 129
TRANSACTIONS OF T IANJ IN UNIVERSITY, vol. 8, no. 1, 2002, pages 40 - 41
"Shin-Jikkenkagaku Koza 9, Bunseki Kagaku II", 1977, MARUZENCOMPANY, LIMITED, pages: 86 - 112
"Jikkenkagaku Koza 20-1, Bunseki Kagaku", 2007, MARUZEN COMPANY, LIMITED, pages: 130 - 151
"Shin-Jikkenkagaku Koza 9, Bunseki Kagaku II", 1977, MARUZEN COMPANY, LIMITED, pages: 60 - 86
"Jikkenkagaku Koza 20-1, Bunseki Kagaku", 2007, MARUZEN COMPANY, LIMITED, pages: 121 - 129
Attorney, Agent or Firm:
SAEKI, Norio et al. (JP)
Norio Saeki (JP)
Norio Saeki (JP)
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