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Patent Searching and Data


Title:
METHOD FOR MANUFACTURING OXADIAZOLE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2017/104782
Kind Code:
A1
Abstract:
In order to provide a method for manufacturing a compound (1) or a pharmaceutically acceptable salt thereof, whereby yield can be improved, cost can be reduced by using an easily obtained, inexpensive starting material and efficiently recovering unnecessary stereoisomers, and environmental burden can be decreased, the present invention is a method for manufacturing a compound represented by formula (1) or a pharmaceutically acceptable salt thereof, the method including a step for obtaining a compound represented by general formula (III) (in which R represents a carboxyl-protecting group) using a compound represented by formula (12) and a compound represented by general formula (II) (in which R represents a carboxyl-protecting group).

Inventors:
TAKEDA TADAHIRO (JP)
KANEDA TAKESHI (JP)
ITOOKA RYO (JP)
HARA MANABU (JP)
KUBOTA KAZUO (JP)
NAITO SHIN (JP)
Application Number:
PCT/JP2016/087486
Publication Date:
June 22, 2017
Filing Date:
December 16, 2016
Export Citation:
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Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C07D271/06; C07C51/43; C07C59/68
Domestic Patent References:
WO2012050151A12012-04-19
WO2013108800A12013-07-25
WO2010067824A12010-06-17
Foreign References:
JPS5829719A1983-02-22
JPS6183144A1986-04-26
Other References:
DATABASE Database [online] 9 August 2013 (2013-08-09), retrieved from STN Database accession no. 1448004-30-5
BOSTROM J. ET AL.: "Oxadiazoles in Medicinal Chemistry", JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, 2012, pages 1817 - 1830, XP055050959, DOI: doi:10.1021/jm2013248
Attorney, Agent or Firm:
ISHIBASHI, Koki et al. (JP)
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