Title:
METHOD FOR MANUFACTURING SUBSTANTIALLY 1FL BODIES SHAPED AS CAPSULES, AND DEVICE USED FOR SAME
Document Type and Number:
WIPO Patent Application WO/2019/078311
Kind Code:
A1
Abstract:
The present invention pertains to an electrospray device that includes a microhole array chip 10, two electrodes 20, 21 provided at a distance from each other so as to face each of the main surfaces of the microhole array chip, and a power supply 30 for applying a voltage between the two electrodes. The present invention pertains to a method for manufacturing bodies shaped as capsules, said method including: filling a space 1 in the device with a liquid being encapsulated; filling a space 2 with a liquid that is poorly soluble in the liquid being encapsulated; applying a pulse wave voltage between two electrodes; causing the liquid being encapsulated to pass through microholes in the microhole array chip; and forming bodies shaped as capsules in the liquid that is poorly soluble in the liquid being encapsulated in the space 2. The present invention is a method for conducting a μL-scale cell-free reaction in capsules in fL-scale IVC, and provides a means whereby fL-scale IVC is conduced in capsules in a manner that is simpler and more efficient than in prior-art methods.
Inventors:
BIYANI MANISH (JP)
TAKAMURA YUZURU (JP)
SHARMA KIRTI (JP)
PHAN TUE TRONG (JP)
MINAMI NORITAKA (JP)
TAKAMURA YUZURU (JP)
SHARMA KIRTI (JP)
PHAN TUE TRONG (JP)
MINAMI NORITAKA (JP)
Application Number:
PCT/JP2018/038900
Publication Date:
April 25, 2019
Filing Date:
October 18, 2018
Export Citation:
Assignee:
JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECH (JP)
International Classes:
B01J13/04
Domestic Patent References:
| WO2002068104A1 | 2002-09-06 |
Foreign References:
| JP2009133687A | 2009-06-18 |
Other References:
ZOUOXIAN MA ET AL.: "Electrospray biodegradable microcapsules loaded with curcumin for drug delivery systems with high bioactivity", THE ROYAL SOCIETY OF CHEMISTRY, vol. 7, no. 3, 16 December 2016 (2016-12-16), pages 1724 - 1734, XP055598037
Attorney, Agent or Firm:
SIKS & CO. (JP)
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