Title:
METHOD AND MARKER FOR THE ISOLATION OF HUMAN MULTIPOTENT HEMATOPOIETIC STEM CELLS
Document Type and Number:
WIPO Patent Application WO2002033043
Kind Code:
A3
Abstract:
The present invention provides a human hematopoietic stem cell surface marker, C1>qp<, which is present on both CD34?-> and CD34<+> stem cells. This marker can be used to advantage in methods for the positive selection of both CD34<-> and CD34<+> stem cell populations.
Inventors:
BONNET DOMINIQUE (GB)
DANET GUENAHEL H (US)
DANET GUENAHEL H (US)
Application Number:
PCT/US2001/032260
Publication Date:
October 10, 2002
Filing Date:
October 18, 2001
Export Citation:
Assignee:
CORIELL INST FOR MEDICAL RES (US)
TRUSTREES OF THE UNIVERSITY OF (US)
BONNET DOMINIQUE (GB)
DANET GUENAHEL H (US)
TRUSTREES OF THE UNIVERSITY OF (US)
BONNET DOMINIQUE (GB)
DANET GUENAHEL H (US)
International Classes:
C07K16/28; C12N5/0789; A61K35/12; (IPC1-7): A61K39/00; C12N5/00; G01N33/53
Foreign References:
| US5965439A | 1999-10-12 |
Other References:
TENNER ET AL.: "Mannose binding protein (MBP) enhances mononuclear phagocyte function via a receptor that contains the 126,00 Mr component of the C1q receptor", IMMUNITY, vol. 3, October 1995 (1995-10-01), pages 485 - 493, XP002058774
NEPOMUCENO R.R.: "cDNA Cloning and expression analysis of C1qRp, the human C1q/MBL/SPA receptor that enhances phagocytosis", J. ALLERGY CLIN. IMMUNOL., vol. 99, no. 1, PART 2, 1997, pages S373, XP002952114
NEPOMUCENO R.R.: "cDNA Cloning and expression analysis of C1qRp, the human C1q/MBL/SPA receptor that enhances phagocytosis", J. ALLERGY CLIN. IMMUNOL., vol. 99, no. 1, PART 2, 1997, pages S373, XP002952114
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