METHOD FOR MASS PRODUCTION OF MOUSE OVUM BASED ON NOVEL SUPEROVULATION-INDUCTION TREATMENT

WIPO Patent Application WO/2016/133195

A1

The purpose of the present invention is to provide a novel method that achieves excellent superovulation-induction efficiency. Specifically, the purpose of the present invention is to provide a method that achieves superior superovulation-induction efficiency compared with conventional methods using equine chorionic gonadotropin (eCG) and human chorionic gonadotropin (hCG). The present invention provides a superovulation-induction method characterized in that an anti-inhibin antibody and equine chorionic gonadotropin (eCG) are simultaneously administered to a female mouse, followed by administration of human chorionic gonadotropin (hCG) thereto.

NAKAGATA NAOMI (JP)
TAKEO TORU (JP)

PCT/JP2016/054838

August 25, 2016

February 19, 2016

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NAT UNIV CORP KUMAMOTO UNIV (JP)

C12N5/075; A01K67/02; C12N5/0735

US20030237104A1

2003-12-25

TAKEO TORU ET AL.: "Reduced Glutathione Enhances Fertility of Forzen/Thawed C57BL/6 Mouse Sperm after Exposure to Methyl-Beta- Cyclodextrin", BIOLOGY OF REPRODUCTION, vol. 85, 2011, pages 1066 - 1072, XP055474933
HASEGAWA AYUMI ET AL.: "Efficient Production of Offspring from Japanese Wild-Derived Strains of Mice (Mus musculus molossinus) by Improved Assisted Reproductive Technologies", BIOLOGY OF REPRODUCTION, vol. 86, 2012, pages 1 - 7, XP055474951
See also references of EP 3260535A4

OSAWA KENICHI (JP)
Ken-ichi Osawa (JP)

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