Title:
METHOD, POLYNUCLEOTIDE, AND KIT FOR ASSESSING RISK OF ONSET OF STOMACH CANCER IN PATIENT AFTER REMOVING HELICOBACTER PYLORI
Document Type and Number:
WIPO Patent Application WO/2024/048753
Kind Code:
A1
Abstract:
Provided is a method for assessing the risk of the onset of stomach cancer in a patient after removing Helicobacter pylori, the method comprising a step for detecting the expression of a KK-LC-1 gene in a stomach tissue sample derived from the patient before removing Helicobacter pylori, wherein positive expression of the KK-LC-1 gene indicates that there is a risk of the onset of stomach cancer in the patient after removing Helicobacter pylori.
Inventors:
FUKUYAMA TAKASHI (JP)
KOBAYASHI NORITADA (JP)
YAMAZAKI TAIGA (JP)
TAKAHASHI YOSHIHITO (JP)
YAMAZAKI HITOSHI (JP)
FUTAWATARI NOBUE (JP)
OTSUKA TOSHIKAZU (JP)
KOIZUMI WASABURO (JP)
ICHIKI YOSHINOBU (JP)
SAKAGUCHI KANAKO (JP)
KOBAYASHI NORITADA (JP)
YAMAZAKI TAIGA (JP)
TAKAHASHI YOSHIHITO (JP)
YAMAZAKI HITOSHI (JP)
FUTAWATARI NOBUE (JP)
OTSUKA TOSHIKAZU (JP)
KOIZUMI WASABURO (JP)
ICHIKI YOSHINOBU (JP)
SAKAGUCHI KANAKO (JP)
Application Number:
PCT/JP2023/031975
Publication Date:
March 07, 2024
Filing Date:
August 31, 2023
Export Citation:
Assignee:
THE KITASATO INST (JP)
International Classes:
C12Q1/6886; C12N15/11; C12Q1/6827; G01N33/574
Domestic Patent References:
| WO2021037399A1 | 2021-03-04 |
Foreign References:
| JP2017195803A | 2017-11-02 | |||
| JP2018512878A | 2018-05-24 |
Other References:
FUKUYAMA TAKASHI, FUTAWATARI NOBUE, YAMAMURA RUI, YAMAZAKI TAIGA, ICHIKI YOSHINOBU, EMA AKIRA, USHIKU HIDEKI, NISHI YATSUSHI, TAKA: "Expression of KK-LC-1, a cancer/testis antigen, at non-tumour sites of the stomach carrying a tumour", SCIENTIFIC REPORTS, vol. 8, no. 1, 1 December 2018 (2018-12-01), pages 6131, XP055805222, DOI: 10.1038/s41598-018-24514-9
DATABASE Nucleotide 21 August 2003 (2003-08-21), ANONYMOUS : "PUJEM31TD ZM_0.6_1.0_KB Zea mays genomic clone ZMMBTa0650E13, genomic survey sequence.", XP093144933, retrieved from NCBI Database accession no. CG180406.
DATABASE Nucleotide 19 June 2003 (2003-06-19), ANONYMOUS : "OGVEZ67TH ZM_0.7_1.5_KB Zea mays genomic clone ZMMBMa0546K14, genomic survey sequence.", XP093144934, retrieved from NCBI Database accession no. CC660145
DATABASE Nucleotide 21 August 2003 (2003-08-21), ANONYMOUS : "PUJEM31TD ZM_0.6_1.0_KB Zea mays genomic clone ZMMBTa0650E13, genomic survey sequence.", XP093144933, retrieved from NCBI Database accession no. CG180406.
DATABASE Nucleotide 19 June 2003 (2003-06-19), ANONYMOUS : "OGVEZ67TH ZM_0.7_1.5_KB Zea mays genomic clone ZMMBMa0546K14, genomic survey sequence.", XP093144934, retrieved from NCBI Database accession no. CC660145
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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