Title:
A METHOD FOR THE PREPARATION OF 2-KETO CARBOXYLIC ACID
Document Type and Number:
WIPO Patent Application WO/2010/139527
Kind Code:
A3
Abstract:
The present invention refers to a method for the preparation of 2-keto carboxylic acid having the general formula R1-CO-COOH, wherein R1 is a branched alkyl group having 3 to 7 carbon atoms, or a salt thereof, comprising a fermentation step wherein a microorganism is grown in a culture medium in order to provide a culture broth containing 2-keto carboxylic acid or a salt thereof.
Inventors:
KARAU ANDREAS (FR)
MORIN NICOLAS (FR)
GERSTMEIR ROBERT (DE)
MORIN NICOLAS (FR)
GERSTMEIR ROBERT (DE)
Application Number:
PCT/EP2010/056345
Publication Date:
March 03, 2011
Filing Date:
May 10, 2010
Export Citation:
Assignee:
EVONIK DEGUSSA GMBH (DE)
KARAU ANDREAS (FR)
MORIN NICOLAS (FR)
GERSTMEIR ROBERT (DE)
KARAU ANDREAS (FR)
MORIN NICOLAS (FR)
GERSTMEIR ROBERT (DE)
International Classes:
C12P7/50
Domestic Patent References:
| WO2006082252A2 | 2006-08-10 |
Foreign References:
| EP1767616A2 | 2007-03-28 |
Other References:
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; T. TABUCHI: "Organic acid fermentation by yeasts. VIII. Accumulation of alpha-ketoisocaproic acid from glucose in cultures of yeasts", XP002614533, Database accession no. 1974:94252
DATABASE WPI Week 198019, Derwent World Patents Index; AN 1980-33558C, XP002614534
DATABASE WPI Week 197742, Derwent World Patents Index; AN 1977-75200Y, XP002614535
R. P. WAGNER ET AL: "The accumulation of keto acids and acetaldehyde by a strain of neurospora inhibited by threonine", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 216, 1955, pages 251 - 262, XP002614536
S POSPISIL ET AL: "Overproduction of 2-ketoisovalerate and momensin production by regulatory mutants of Streptococcus cinnamonensis resistant to 2-ketobutyrate and amino acids", FEMS MICROBIOLOGY LETTERS, vol. 172, no. 2, 1999, pages 197 - 204, XP002614537
H. C. BECK ET AL: "Catabolism of leucine to branched -chain fatty acids jn Staphylococcus xylosus", JOURNAL OF APPLIED MICROBIOLOGY, vol. 96, no. 5, 2004, pages 1185 - 1193, XP002614538
DATABASE WPI Week 198019, Derwent World Patents Index; AN 1980-33558C, XP002614534
DATABASE WPI Week 197742, Derwent World Patents Index; AN 1977-75200Y, XP002614535
R. P. WAGNER ET AL: "The accumulation of keto acids and acetaldehyde by a strain of neurospora inhibited by threonine", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 216, 1955, pages 251 - 262, XP002614536
S POSPISIL ET AL: "Overproduction of 2-ketoisovalerate and momensin production by regulatory mutants of Streptococcus cinnamonensis resistant to 2-ketobutyrate and amino acids", FEMS MICROBIOLOGY LETTERS, vol. 172, no. 2, 1999, pages 197 - 204, XP002614537
H. C. BECK ET AL: "Catabolism of leucine to branched -chain fatty acids jn Staphylococcus xylosus", JOURNAL OF APPLIED MICROBIOLOGY, vol. 96, no. 5, 2004, pages 1185 - 1193, XP002614538
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