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Patent Searching and Data


Title:
METHOD FOR THE PREPARATION OF CRYSTALLINE TETRAHYDROBENZOTHIEPINES
Document Type and Number:
WIPO Patent Application WO2003022804
Kind Code:
A3
Abstract:
Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of single crystals of ASBT inhibitors having high purity and low levels of solvent impurities.

Inventors:
MUDIPALLI PARTHA S (US)
POZZO MARK J (US)
PARK JUNG MIN (US)
Application Number:
US0226877W
Publication Date:
November 20, 2003
Filing Date:
August 23, 2002
Export Citation:
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Assignee:
G.D. SEARLE LLC
MUDIPALLI, PARTHA, S.
POZZO, MARK, J.
PARK, JUNG MIN
International Classes:
A61K31/4995; A61P1/16; A61P3/06; A61P43/00; B01D9/02; C07D337/08; C07D487/08; (IPC1-7): C07D409/10; C07D409/12; C07D337/08
Foreign References:
US5994391A1999-11-30
US6262277B12001-07-17
Other References:
See also references of EP 1425279A2
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