METHOD AND PREPARATION FOR PREVENTING CASUALTY CAUSED BY IODINE RADIONUCLIDES AND OPTIMISING IODINE METABOLISM IN A POSTPROPHYLAXIS PERIOD

Title:

METHOD AND PREPARATION FOR PREVENTING CASUALTY CAUSED BY IODINE RADIONUCLIDES AND OPTIMISING IODINE METABOLISM IN A POSTPROPHYLAXIS PERIOD

Document Type and Number:

WIPO Patent Application WO/2004/026322

Kind Code:

A1

Abstract:

The invention relates to medicine and veterinary. The quantity of the inventive preparation for preventing casualty caused by iodine radionuclides and optimising the iodine metabolism in a postprophylaxis period injected into the human and animal organism is higher than a physiological need. Said preparation comprises synthetic or natural organic compounds containing covalently bound iodine selected from the following groups: carbonic acids, unsaturated fat acids, lipids, terpene, alkanets, terpenoids, isoprenes, peptides, polypeptides, amino acids, protein hydrolysates, polypeptide hydrolysates, vegetable proteins, animal proteins, microbiological proteins, a mixture of lipids and unsaturated fat acids, a mixture of isoprenes and terpenes, a mixture of isoprenes and protein hydrolysates, a mixture of isoprenes and unsaturated fat acids, a mixture of vegetable, animal and microbiological proteins, a mixture of vegetable and animal proteins, a mixture of animal and microbiological proteins and a mixture of vegetable and microbiological proteins. Iodine is also covalently bound in the 5^th and 3d or in the 3d position of the phenolic cycle and in the 3d position of an imidazole cycle in proteins, peptides, polypeptides, amino acids and in polypeptide and protein hydrolysates. The amino acids and proteins are selected from the group of amino acids and proteins which are devoid of hormonal and thyroid activity and produced in conditions excluding the condensation of tyrosine nucleus.

Inventors:

ANDREICHUK VASILY PETROVICH (RU)
ANDREICHUK ELENA VIKTOROVNA (RU)
LYSENKO NIKOLAI PETROVICH (RU)
ROGOZHINA LARISA VASILEVNA (RU)

Application Number:

PCT/RU2003/000409

Publication Date:

April 01, 2004

Filing Date:

September 17, 2003

Export Citation:

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Assignee:

ANDREICHUK VASILY PETROVICH (RU)
ANDREICHUK ELENA VIKTOROVNA (RU)
LYSENKO NIKOLAI PETROVICH (RU)
ROGOZHINA LARISA VASILEVNA (RU)

International Classes:

A61K31/02; A61K31/19; A61K31/215; A61K31/33; A61K38/16; A61P3/02; A61P5/16; (IPC1-7): A61K33/18; A61K31/19; A61K31/215; A61K31/33; A61K38/01; A61K38/02; A61P3/02; A61P5/16

Foreign References:

RU2163127C1	2001-02-20
RU2161000C1	2000-12-27
RU2164144C1	2001-03-20
RU2164406C2	2001-03-27
RU2038028C1	1995-06-27

Other References:

VERGER P. ET AL.: "Jodine kinetics and effectiveness of stable iodine prophylaxis after intake of radioactive iodine: A review", THYROID, vol. 11, no. 4, April 2001 (2001-04-01), pages 353 - 360

Attorney, Agent or Firm:

Serpkova, Natalia Anatolievna (Tsvetnoi bulvar 22-1, 6 etaz, Moscow 1, RU)

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