Title:
METHOD FOR PREPARING 3,3',4,4'-TETRAAMINOBIPHENYL
Document Type and Number:
WIPO Patent Application WO/2022/199226
Kind Code:
A1
Abstract:
A method for preparing 3,3',4,4'-tetraaminobiphenyl, the method comprising the following steps: subjecting 4,4'-biphenol and N,N-dimethylsulfamoyl chloride to an esterification reaction in a specified solvent at 40-70°C to obtain 4,4'-biphenyl bis(N,N-dimethylaminosulfonate) as a first intermediate; subjecting the 4,4'-biphenyl bis(N,N-dimethylaminosulfonate) to a chlorination reaction with a chlorinating reagent under acidic conditions to obtain 3,3'-dichloro-4,4'-biphenyl bis(N,N-dimethylaminosulfonate) as a second intermediate; subjecting the second intermediate 3,3'-dichloro-4,4'-biphenyl bis(N,N-dimethylaminosulfonate) to an ammonolysis reaction with an ammoniation reagent in the presence of a combined catalyst to obtain a crude product of 3,3',4,4'-tetraaminobiphenyl, wherein a mixture of proline, a cuprous salt and a phase transfer catalyst is a first catalyst; and subjecting the crude product of 3,3',4,4'-tetraaminobiphenyl to a post-treatment to obtain a purified 3,3',4,4'-tetraaminobiphenyl product. In the present invention, 4,4'-biphenol is used as a raw material, a brand-new synthesis route is used, the product purity is high, and pollution of three kinds of waste is reduced.
Inventors:
LING YUN (CN)
LI YONGFANG (CN)
WANG KUN (CN)
CHEN LIZHU (CN)
YIN WEI (CN)
ZHANG JINYING (CN)
LI YONGFANG (CN)
WANG KUN (CN)
CHEN LIZHU (CN)
YIN WEI (CN)
ZHANG JINYING (CN)
Application Number:
PCT/CN2022/071586
Publication Date:
September 29, 2022
Filing Date:
January 12, 2022
Export Citation:
Assignee:
INSIGHT FINECHEM CO LTD (CN)
HUBEI HUIDA HIGH TECH CO LTD (CN)
HUBEI HUIDA HIGH TECH CO LTD (CN)
International Classes:
C07C211/50; C07C209/22
Foreign References:
| CN108191674A | 2018-06-22 | |||
| JP2010083909A | 2010-04-15 | |||
| CN102030726A | 2011-04-27 | |||
| CN1580038A | 2005-02-16 | |||
| CN102173994A | 2011-09-07 | |||
| JP2010083809A | 2010-04-15 | |||
| TWI623512B | 2018-05-11 | |||
| CN108218711A | 2018-06-29 | |||
| CN112920054A | 2021-06-08 |
Other References:
YANG ZHONGMIN: "Synthesis of 4,4'-Bis(trifluoromethyl)-2,2'-diaminobiphenyl", INNER MONGOLIAN PETROCHEMICAL INDUSTRY, INNER MONGOLIA INSTITUTE OF CHEMICAL ENGINEERING; INNER MONGOLIA INSTITUTE OF CHEMICAL ENGINEERING, HOHHOT , INNER MONGOLIA AUTONOMOUS REGION, no. 11, 31 December 2015 (2015-12-31), Hohhot , Inner Mongolia Autonomous Region , pages 24 - 26, XP055970522, ISSN: 1006-7981
CUI YUMIN, FAN SHAOHUA, SHAN DEJIE: "Synthesis of 3,3′-Dichloro-4,4-diaminophenyl benzene", HUA HSUEH TUNG PAO - CHEMICAL BULLETIN, ZHONGGUO KEXUEYUAN HUAXUE YANJIUSUO, CN, no. 11, 31 December 2001 (2001-12-31), CN , XP055970519, ISSN: 0441-3776, DOI: 10.14159/j.cnki.0441-3776.2001.11.009
RUAN JINGBO, ZHANG MEI-ZHONG, LU HUANG-MING: "Synthesis of 2,2', 5,5'-tetraaminobiphenyl", CHEMICAL ENTERPRISE MANAGEMENT, 31 May 2020 (2020-05-31), pages 176 - 177, XP055970516
CUI YUMIN, FAN SHAOHUA, SHAN DEJIE: "Synthesis of 3,3′-Dichloro-4,4-diaminophenyl benzene", HUA HSUEH TUNG PAO - CHEMICAL BULLETIN, ZHONGGUO KEXUEYUAN HUAXUE YANJIUSUO, CN, no. 11, 31 December 2001 (2001-12-31), CN , XP055970519, ISSN: 0441-3776, DOI: 10.14159/j.cnki.0441-3776.2001.11.009
RUAN JINGBO, ZHANG MEI-ZHONG, LU HUANG-MING: "Synthesis of 2,2', 5,5'-tetraaminobiphenyl", CHEMICAL ENTERPRISE MANAGEMENT, 31 May 2020 (2020-05-31), pages 176 - 177, XP055970516
Attorney, Agent or Firm:
WISEAST INTELLECTUAL PROPERTY LAW FIRM (CN)
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