Title:
METHOD FOR PREPARING ACE INHIBITORY PEPTIDES FROM HAIRTAIL LEFTOVERS
Document Type and Number:
WIPO Patent Application WO/2014/194530
Kind Code:
A1
Abstract:
Disclosed in the present invention is a method for preparing ACE (Angiotensin-Converting Enzyme) inhibitory peptides from hairtail leftovers. The ACE inhibitory peptides are obtained by the steps of cleaning and mixing the hairtail leftovers with water, homogenization, enzymolysis and plate-and-frame filtration, intercepting small molecules of less than 3000 Da by ultrafiltration, and drying. Sephadex G-15 and RP-HPLC (Reverse Phase High-Performance Liquid Chromatography) can further be employed for two-step separation and purification to obtain high-purity ACE inhibitory peptides. The method of the present invention can change wastes into valuables by converting low-value hairtail leftovers into high-value ACE inhibitory peptides, achieve full use of resources, and has the advantages of easy process route, simplicity in operation, highly developed equipment used in the method, low investment cost and high recovery rate of the ACE inhibitory peptides.
More Like This:
Inventors:
HE XIONGLEI (CN)
ZHU WEI (CN)
ZHU WEI (CN)
Application Number:
PCT/CN2013/077002
Publication Date:
December 11, 2014
Filing Date:
June 08, 2013
Export Citation:
Assignee:
WITHYOU BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12P21/00; A61P9/12
Foreign References:
| CN101130800A | 2008-02-27 | |||
| CN101240312A | 2008-08-13 |
Other References:
WANG, JINLING ET AL.: "Screening of Aquatic Protein Material for ACEIIP Producing by Enzyme Hydrolysis", JOURNAL OF CHINESE INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY, vol. 9, no. 3, June 2009 (2009-06-01), pages 111 - 116
XIAO, HONG ET AL.: "Antihypertensive Peptides Derived From Food Proteins and its Research Advances", FOOD RESEARCH AND DEVELOPMENT, vol. 25, no. 5, October 2004 (2004-10-01), pages 3 - 7
WU, WEILIANG ET AL.: "The Physiological Function and Research Progress of Angiotensin-I-converting Enzyme Inhibitory Petides", MODERN FOOD SCIENCE AND TECHNOLOGY, vol. 22, no. 3, July 2006 (2006-07-01), pages 251 - 254
LIN HUIMIN ET AL.: "Preparing Ferrous Chelating of Hairtail Protein Hydrolysate (Fe-HPH) with High Antibacterial and Antioxidant Activity by URrafiltration", J OURNAL OF CHINESE INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY, vol. 12, no. 6, June 2012 (2012-06-01), pages 16 - 21
XIAO, HONG ET AL.: "Antihypertensive Peptides Derived From Food Proteins and its Research Advances", FOOD RESEARCH AND DEVELOPMENT, vol. 25, no. 5, October 2004 (2004-10-01), pages 3 - 7
WU, WEILIANG ET AL.: "The Physiological Function and Research Progress of Angiotensin-I-converting Enzyme Inhibitory Petides", MODERN FOOD SCIENCE AND TECHNOLOGY, vol. 22, no. 3, July 2006 (2006-07-01), pages 251 - 254
LIN HUIMIN ET AL.: "Preparing Ferrous Chelating of Hairtail Protein Hydrolysate (Fe-HPH) with High Antibacterial and Antioxidant Activity by URrafiltration", J OURNAL OF CHINESE INSTITUTE OF FOOD SCIENCE AND TECHNOLOGY, vol. 12, no. 6, June 2012 (2012-06-01), pages 16 - 21
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
广州嘉权专利商标事务所有限公司 (CN)
广州嘉权专利商标事务所有限公司 (CN)
Download PDF:
Previous Patent: NOVEL AIRFLOW PRESSURE-REDUCING DEVICE AND AIRFLOW PRESSURE-REDUCING METHOD
Next Patent: REFRIGERATION DEVICE
Next Patent: REFRIGERATION DEVICE