Title:
METHOD OF PREPARING AUTOLOGOUS CELLS AND METHOD OF USE FOR THERAPY
Document Type and Number:
WIPO Patent Application WO/2010/127342
Kind Code:
A3
Abstract:
A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium which can be used in a clinical setting, and a business method for performing such expansions in the future as a service for patients. A method for expanding mesenchymal cells derived from autologous bone marrow in autologous culture medium including a diagnostic kit for the autologous cell therapy to determine whether a patient will respond to the autologous cell therapy for treatment of a disease, in which said kit comprising a system for detecting gene and protein expression comprising at least two isolated DNA molecules wherein each isolated DNA molecule detects expression of a gene that is differentially expressed in the tissue of the patient that is intended to be the source of the autologous cell therapy.
Inventors:
ROUY DIDIER (US)
ALTMAN PETER A
KOZINER BENJAMIN
ALTMAN PETER A
KOZINER BENJAMIN
Application Number:
PCT/US2010/033378
Publication Date:
April 07, 2011
Filing Date:
May 03, 2010
Export Citation:
Assignee:
BIOCARDIA INC (US)
ROUY DIDIER (US)
ALTMAN PETER A
KOZINER BENJAMIN
ROUY DIDIER (US)
ALTMAN PETER A
KOZINER BENJAMIN
International Classes:
C12Q1/68; A61K35/12; C12N5/077; C12Q1/02
Foreign References:
| US20070037144A1 | 2007-02-15 | |||
| US20060003365A1 | 2006-01-05 | |||
| US20090035286A1 | 2009-02-05 |
Other References:
STRAUER, B. E. ET AL.: "Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease", J. AM. COLL. CARDIOL., vol. 46, no. 9, 1 November 2005 (2005-11-01), pages 1651 - 1658, XP027719484
VANDERVELDE, S. ET AL.: "Stem cell-related cardiac gene expression early after murine myocardial infarction", CARDIOVASC. RES., vol. 73, no. 4, 1 March 2007 (2007-03-01), pages 783 - 793, XP005914965
See also references of EP 2425022A4
VANDERVELDE, S. ET AL.: "Stem cell-related cardiac gene expression early after murine myocardial infarction", CARDIOVASC. RES., vol. 73, no. 4, 1 March 2007 (2007-03-01), pages 783 - 793, XP005914965
See also references of EP 2425022A4
Attorney, Agent or Firm:
CROCKETT, K., David (Suite 200Mission Viejo, CA, US)
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