Title:
METHOD FOR PREPARING CELL GROWTH SCAFFOLD HAVING STRUCTURAL MEMORY PROPERTIES
Document Type and Number:
WIPO Patent Application WO/2017/107997
Kind Code:
A1
Abstract:
Disclosed is a method for preparing a cell growth scaffold having structural memory properties, comprising the step of preparing a microfibrillated or flocculent acellular tissue matrix material, the steps of preparing acidified hydrogel-like acellular tissue matrix particles, proportionally mixing the prepared microfibrillated or flocculent acellular tissue matrix material and the acidified hydrogel-like acellular tissue matrix particles, followed by injection molding, a freezing treatment, a radiation treatment, and ultimately preparing same into a porous cell growth scaffold that can be stored at room temperature. The cell growth scaffold prepared from the method is a porous cell growth scaffold without chemical crosslinking, having a biological activity, a stable three dimensional structure and structural memory features. The cell growth scaffold has a good biocompatibility and complete biodegradability, supports the growth of cells and the growth of tissues and organs in vitro and in vivo, and is suitable for the repair of soft tissue trauma and damage.
Inventors:
SUN WENQUAN (CN)
HUANG SENLI (CN)
HUANG SENLI (CN)
Application Number:
PCT/CN2016/111926
Publication Date:
June 29, 2017
Filing Date:
December 24, 2016
Export Citation:
Assignee:
BEIJING RUIJIAN GAOKE BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61L27/24; A61L27/36; A61L27/56; A61L27/58
Domestic Patent References:
| WO2012006390A1 | 2012-01-12 |
Foreign References:
| CN104107456A | 2014-10-22 | |||
| CN105169483A | 2015-12-23 | |||
| CN1407002A | 2003-04-02 | |||
| CN103432627A | 2013-12-11 | |||
| CN104144715A | 2014-11-12 | |||
| US20120263763A1 | 2012-10-18 |
Other References:
See also references of EP 3369439A4
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