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Patent Searching and Data


Title:
METHOD FOR PREPARING CRYSTAL FORM OF AZACITIDINE
Document Type and Number:
WIPO Patent Application WO/2019/129260
Kind Code:
A1
Abstract:
The present invention relates to a method for preparing a crystal form of azacitidine. The present invention relates to a method for preparing a crystal form I of azacitidine. DMSO is used as a solvent, and a mixed alcohol solvent is used as an anti-solvent. The prepared crystal form is single, features good purity and no mixed crystals, has low solvent residues, and is suitable for industrial application and production.

Inventors:
LIN, Qing (Economic and Technological Development Zone, Lianyungang, Jiangsu 7, 222047, CN)
HE, Lei (Economic and Technological Development Zone, Lianyungang, Jiangsu 7, 222047, CN)
YU, Jun (Economic and Technological Development Zone, Lianyungang, Jiangsu 7, 222047, CN)
Application Number:
CN2018/125314
Publication Date:
July 04, 2019
Filing Date:
December 29, 2018
Export Citation:
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Assignee:
JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (Economic and Technological Development Zone, Lianyungang, Jiangsu 7, 222047, CN)
International Classes:
C07H19/12
Domestic Patent References:
WO2004082619A22004-09-30
WO2004082822A22004-09-30
WO2009016617A22009-02-05
Foreign References:
CN102850418A2013-01-02
Attorney, Agent or Firm:
GE CHENG & CO.,LTD. (David W. CHENG, Level 19 Tower E3, The Towers, Oriental Plaza, No.1, East Chang An Avenue, Dongcheng District, Beijing 8, 100738, CN)
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