Title:
METHOD FOR PREPARING CRYSTALLINE FORM A OF P1, P4-DI(URIDINE 5'-)TETRAPHOSPHATE SODIUM SALT TETRAHYDRATE
Document Type and Number:
WIPO Patent Application WO/2021/172957
Kind Code:
A1
Abstract:
The present invention relates to a method for preparing a crystalline form A of P1, P4-di(uridine 5'-)tetraphosphate sodium salt tetrahydrate and a crystalline form A of P1, P4-di(uridine 5'-)tetraphosphate sodium salt tetrahydrate prepared thereby, wherein the crystalline form A of P1, P4-di(uridine 5'-)tetraphosphate sodium salt tetrahydrate maintains a moisture content of about 5.0 to 11.0 wt%, and thus has been proved to be a novel crystalline form different from conventional crystalline forms. According to the method of the present invention, the crystalline form A of P1, P4-di(uridine 5'-)tetraphosphate sodium salt tetrahydrate can be conveniently and stably prepared without the use of a process unsuitable for mass production and a separate apparatus, and thus the crystalline form A can be mass-produced more efficiently.
Inventors:
LEE SUNG RYOUNG (KR)
LEE MYEONG SEOK (KR)
KANG HEUNG MO (KR)
CHOI IN SUK (KR)
LEE MYEONG SEOK (KR)
KANG HEUNG MO (KR)
CHOI IN SUK (KR)
Application Number:
PCT/KR2021/002510
Publication Date:
September 02, 2021
Filing Date:
February 26, 2021
Export Citation:
Assignee:
CKD BIO CORP (KR)
International Classes:
C07F9/09
Domestic Patent References:
| WO1999005155A2 | 1999-02-04 | |||
| WO1996040059A1 | 1996-12-19 |
Foreign References:
| KR20020013471A | 2002-02-20 | |||
| KR20190051850A | 2019-05-15 | |||
| US7759322B2 | 2010-07-20 |
Attorney, Agent or Firm:
KONG, Byung Wook (KR)
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