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Title:
METHOD FOR PREPARING DEOXYCHOLIC ACID
Document Type and Number:
WIPO Patent Application WO/2016/165496
Kind Code:
A1
Abstract:
Disclosed is method for preparing a deoxycholic acid or ester thereof or pharmaceutically acceptable salt thereof. The compound is suitable for removing fat deposition.

Inventors:
LIN, Chenggang (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
GUI, Li (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
CHEN, Pan (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
WANG, Zhixuan (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
GUAN, Tongwei (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
YIN, Yuanyuan (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
LU, Yuling (6th Fl, F6 Building No. 9 Weidi Road, Qixia Distric, Nanjing Jiangsu 6, 210046, CN)
Application Number:
CN2016/074662
Publication Date:
October 20, 2016
Filing Date:
February 26, 2016
Export Citation:
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Assignee:
NORATECH PHARMACEUTICALS, INC. (12F.-5, No.760 Sec. 4, Bade Rd., Songshan Dist, Taipei City Taiwan, 10567, CN)
International Classes:
C07J9/00; C07J1/00; C07J21/00
Foreign References:
CS226540B11984-04-16
CN102060902A2011-05-18
CN1257077A2000-06-21
CN1793159A2006-06-28
Other References:
RUFF, A. ET AL.: "Steroids . VI. Partial synthesis of 9,11-dehydroprogesterone", JOURNAL OF THE CHEMICAL SOCIETY, 1 January 1953 (1953-01-01), pages 3683 - 3690, XP055322471
HARBURN, JAMES J. ET AL.: "Synthesis of novel steroidal inhibitors of HIV-1 protease", TETRAHEDRON, vol. 54, no. 39, 31 December 1998 (1998-12-31), pages 11907 - 11924, XP004133366
MITSUHASHI, HIROSHI ET AL.: "C-Nor-D-homosteroids. VIII. C-nor-D-homo-rearrangement of cholanic acid and its derivatives", TETRAHEDRON, vol. 24, no. 6, 31 December 1968 (1968-12-31), pages 2789 - 2794, XP055322486
ZHAO, ZHIGANG ET AL.: "Design and Synthesis of Novel Deoxycholic Acid-Based Chiral Molecular Tweezers Containing Unsymmetrically Disubstituted Urea Unit", JOURNAL OF ORGANIC CHEMISTRY, vol. 28, no. 7, 31 December 2008 (2008-12-31), pages 1233 - 1237
CHEN, JING ET AL.: "Synthesis of Molecular Clefts Based on Deoxycholic Acid under Microwave Irradiation", CHINESE JOURNAL OF SYNTHETIC CHEMISTRY, vol. 16, no. 1, 31 December 2008 (2008-12-31), pages 28 - 32, XP009507339
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (David W. Cheng, Level 19 Tower E3, The Towers, Oriental Plaza,No.1, East Chang An Avenue, Dongcheng District, Beijing 8, 100738, CN)
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