METHOD FOR PREPARING DIOL COMPOUND AT HIGH YIELD USING GLYCEROL FERMENTATION MICROORGANISM VARIANT

WIPO Patent Application WO/2013/012293

A3

The present invention relates to a method for preparing a diol compound from glycerol using a variant strain, and more specifically to a method for producing 1,3-propanediol and 2,3-butanediol at a high yield by using a variant of a microorganism capable of fermenting glycerol that lacks a gene for coding lactate dehydrogenase. According to the present invention, the production amount of 1,3-propanediol and 2,3-butanediol can be significantly improved through a novel culturing method of a glycerol fermentation microorganism variant.

KIM CHUL HO (KR)
SEO JEONG-WOO (KR)
OH BAEK ROCK (KR)
HEO SUN YEON (KR)

PCT/KR2012/005832

March 28, 2013

July 20, 2012

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KOREA RES INST OF BIOSCIENCE (KR)
KIM CHUL HO (KR)
SEO JEONG-WOO (KR)
OH BAEK ROCK (KR)
HEO SUN YEON (KR)

C12P7/02; C12N1/20; C12P7/18; C12R1/22

US20100137655A1	2010-06-03
KR20100102928A	2010-09-27

XU, Y. ET AL.: "Metabolism in 1,3-Propanediol Fed-Batch Fermentation by a D-Lactate Deficient Mutant of Klebsiella pneumoniae", BIOTECHNOLOGY & BIOENGINEERING, vol. 104, no. 5, 2009, pages 965 - 972
YANG, G. ET AL.: "Fermentation of 1,3-propanediol by a lactate deficient mutant of Klebsiella oxytoca under microaerobic conditions", APPL MICROBIOL BIOTECHNOL, vol. 73, 2007, pages 1017 - 1024

LEE, Cheo Young (Yeosam Bldg.648-23, Yeoksam-dong, Gangnam-gu, Seoul 135-080, KR)

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