Title:
METHOD FOR PREPARING L-ERGOTHIONEINE-CONTAINING COSMETIC STOCK SOLUTION BY MEANS OF FERMENTING HERICIUM ERINACEUS
Document Type and Number:
WIPO Patent Application WO/2020/177390
Kind Code:
A1
Abstract:
A method for preparing an L-ergothioneine-containing cosmetic stock solution by means of fermenting Hericium erinaceus, the method comprising the following steps: step 1: inoculating Hericium erinaceus hyphae into a liquid seed culture medium for culturing to obtain a seed solution; step 2: inoculating the seed solution into a fermentation culture medium for fermentation and adding an L-ergothioneine precursor substance, and fermenting to an end point to obtain a fermentation broth; step 3: processing the fermentation broth containing mycelium to obtain an L-ergothioneine-containing fermentation stock solution and using same as the L-ergothioneine-containing cosmetic stock solution. The described stock solution product contains higher than 300 mg/L of L-ergothioneine, and has strong antioxidant, anti-radiation and anti-inflammatory effects; moreover, the described stock solution can be added as a raw material into water, milk, creams, and so on, and is widely applied in the field of cosmetics.
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Inventors:
LU ZHEN (CN)
WEI YUJIE (CN)
JIA YUQIAN (CN)
SUN YUANJUN (CN)
SHI YANLI (CN)
GUO XUEPING (CN)
LUAN YIHONG (CN)
WEI YUJIE (CN)
JIA YUQIAN (CN)
SUN YUANJUN (CN)
SHI YANLI (CN)
GUO XUEPING (CN)
LUAN YIHONG (CN)
Application Number:
PCT/CN2019/118949
Publication Date:
September 10, 2020
Filing Date:
November 15, 2019
Export Citation:
Assignee:
BLOOMAGE BIOTECHNOLOGY CORP LTD (CN)
SHANDONG BLOOMAGE HYINC BIOPHARM CORPORATION LTD (CN)
SHANDONG BLOOMAGE HYINC BIOPHARM CORPORATION LTD (CN)
International Classes:
A61K8/9728; A61K8/49; A61Q17/04; A61Q19/00; A61Q19/08; C12P17/10; C12R1/645
Foreign References:
| CN109939027A | 2019-06-28 | |||
| CN109938332A | 2019-06-28 | |||
| CN109439553A | 2019-03-08 | |||
| CN109439701A | 2019-03-08 | |||
| CN103184246A | 2013-07-03 | |||
| CN108289422A | 2018-07-17 | |||
| CN106831596A | 2017-06-13 | |||
| CN105296559A | 2016-02-03 | |||
| CN102978121A | 2013-03-20 |
Other References:
CHEN, S. Y. ET AL.: "Contents of lovastatin， γ-aminobutyric acid and ergothioneine in mushroom fruiting bodies and mycelia.", LWT-FOOD SCIENCE AND TECHNOLOGY, vol. 47, 31 December 2012 (2012-12-31), XP055576095, DOI: 20191212103414Y
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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