Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
THE METHOD OF PREPARING OF N-N-ALKYL BENZOYL-2-SULFONYLENDOIMINE
Document Type and Number:
WIPO Patent Application WO/2003/074503
Kind Code:
A1
Abstract:
The present invention relates to a method of preparing of N-n-alkyl benzoyl-2-sulfonylendoimine, in which sodium ortho-benzosulfimide and n-alkyl halide react in organic solvent in the presence of efficient amount of phase transfer catalyst, which is characterized in that sodium ortho-benzosulfimide contains crystal water and/or absorbed moisture, the reaction is carried out at the boiling point of the solvent or higher, and the absorbed moisture and crystal water are removed from the raw materials uninterruptedly during the reaction. Compared to the prior art, there is no need to crush the raw materials, no need to pre-remove the crystal water and/or absorbed moisture from the raw materials with high temperature heating in this method and it can achieve short dehydrating time, high yield and high product purity.

Inventors:
Rong, Jun (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Lingchong YU. (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Jiang, Guohua (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Liu, Zhongmin (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Application Number:
PCT/CN2002/000265
Publication Date:
September 12, 2003
Filing Date:
April 17, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Rong, Jun (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Lingchong YU. (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Jiang, Guohua (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
Liu, Zhongmin (Chemical Department Beijing Normal University, Xinjiekouwai District, Beijing 5, 10087, CN)
International Classes:
C07D275/06; (IPC1-7): C07D265/06; A61K47/22
Foreign References:
CN1285224A
JPS5618970A
JPS5618971A
US5512589A
Other References:
MA CHEN ET AL.: 'Study of N-alkylation of saccharin catalyzed by potassium fluoride-alumina' HUAXUE YANJIU vol. 9, no. 3, 1998, pages 40 - 42
TU JUNLI ET AL.: 'A novel method for cyanomethylation of imides and benzoic sulfimide' YOUJI HUAXUE no. 2, 1985, pages 134 - 137
Attorney, Agent or Firm:
KANGXIN & PARTNERS (Suite 2313, Xinlong Mansion A33 Erlongl, Xicheng District Beijing 2, 10003, CN)
Download PDF: