Title:
METHOD FOR PREPARING N-FORMYL AMIDE COMPOUND UNDER CATALYSIS OF VISIBLE LIGHT
Document Type and Number:
WIPO Patent Application WO/2023/240790
Kind Code:
A1
Abstract:
Disclosed in the present invention is a method for preparing an N-formyl amide compound under the catalysis of visible light. In the method, an LED lamp is used as a light source to provide energy, economical and easily available secondary and tertiary amides are used as reaction substrates, copper chloride is used as a catalyst, oxygen is used as an oxidizing agent, commercially available hydrochloric acid is used as an additive, and nitromethane is used as a solvent. Compared with the prior art, the method of the present invention has the following advantages: 1) a green, mild and environment-friendly reaction mode using visible light for catalysis is adopted; 2) the reaction system is simple, the substrate range is broad, and aromatic and aliphatic amides are all applicable to the method; 3) oxygen serves as a green oxidizing agent; 4) the reaction yield is high; 5) the operation is simple; and 6) the raw materials are inexpensive and easily available.
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Inventors:
WAN XIAOBING (CN)
LIAN PENGCHENG (CN)
LI RUYI (CN)
WAN XIAO (CN)
XIANG ZIXIN (CN)
LI MINGGANG (CN)
LIAN PENGCHENG (CN)
LI RUYI (CN)
WAN XIAO (CN)
XIANG ZIXIN (CN)
LI MINGGANG (CN)
Application Number:
PCT/CN2022/113976
Publication Date:
December 21, 2023
Filing Date:
August 22, 2022
Export Citation:
Assignee:
UNIV SOOCHOW (CN)
International Classes:
C07C231/08; C07C231/12; C07C231/14; C07C233/90; C07C233/91
Foreign References:
| KR20090090457A | 2009-08-26 | |||
| CN113717071A | 2021-11-30 |
Other References:
MEI CHONG, HU YIXIN, LU WENJUN: "Visible-Light-Driven Oxidation of N-Alkylamides to Imides Using Oxone/H2O and Catalytic KBr", SYNTHESIS, GEORG THIEME VERLAG, STUTTGART, DE., vol. 50, no. 15, 1 August 2018 (2018-08-01), STUTTGART, DE. , pages 2999 - 3005, XP093118230, ISSN: 0039-7881, DOI: 10.1055/s-0036-1591575
XU LIANG, ZHANG SUHONG, TRUDELL MARK L.: "Novel chromium(vi) catalyzed oxidation of N-alkylamides to imides with periodic acid", CHEMICAL COMMUNICATIONS, ROYAL SOCIETY OF CHEMISTRY, UK, no. 14, 1 January 2004 (2004-01-01), UK , pages 1668, XP093118235, ISSN: 1359-7345, DOI: 10.1039/b404823g
XU LIANG, ZHANG SUHONG, TRUDELL MARK L.: "Novel chromium(vi) catalyzed oxidation of N-alkylamides to imides with periodic acid", CHEMICAL COMMUNICATIONS, ROYAL SOCIETY OF CHEMISTRY, UK, no. 14, 1 January 2004 (2004-01-01), UK , pages 1668, XP093118235, ISSN: 1359-7345, DOI: 10.1039/b404823g
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT AND TRADEMARK AGENCY, LTD (CN)
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