Title:
METHOD FOR PREPARING NON-CHIMERIC GENE KNOCKOUT ANIMAL BASED ON CRISPR/CAS9 TECHNOLOGY
Document Type and Number:
WIPO Patent Application WO/2018/177351
Kind Code:
A1
Abstract:
Provided are a cocktail-style CRISPR/Cas9 system (C-CRISPR) and a method for preparing a gene knockout animal, the gene function of which is completely knocked out or mostly knocked out, by using the system.
Inventors:
YANG HUI (CN)
XIONG ZHIQI (CN)
SUN QIANG (CN)
ZUO ERWEI (CN)
XIONG ZHIQI (CN)
SUN QIANG (CN)
ZUO ERWEI (CN)
Application Number:
PCT/CN2018/081016
Publication Date:
October 04, 2018
Filing Date:
March 29, 2018
Export Citation:
Assignee:
SHANGHAI INST BIOLOGICAL SCIENCES CAS (CN)
International Classes:
C12N15/90; C12N15/89
Domestic Patent References:
| WO2016133165A1 | 2016-08-25 |
Foreign References:
| CN105400810A | 2016-03-16 |
Other References:
LIU, ZHIGUO: "Research Progress on CRISPR/Cas9 Mediated Genome Editing", CHINESE JOURNAL OF ANIMAL AND VETERINARY SCIENCES, vol. 45, no. 10, 15 October 2014 (2014-10-15), pages 1567 - 1581, ISSN: 0366-6964
CONG, L ET AL.: "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, vol. 339, no. 6121, 15 February 2013 (2013-02-15), pages 819 - 823, XP055067741, ISSN: 0036-8075
CONG, L ET AL.: "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, vol. 339, no. 6121, 15 February 2013 (2013-02-15), pages 819 - 823, XP055067741, ISSN: 0036-8075
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
Download PDF: