METHOD FOR PREPARING NOVEL LONG-ACTING HUMAN GROWTH HORMONE MONOMER

Title:

METHOD FOR PREPARING NOVEL LONG-ACTING HUMAN GROWTH HORMONE MONOMER

Document Type and Number:

WIPO Patent Application WO/2014/081225

Kind Code:

A1

Abstract:

The present invention relates to: a method for preparing a high-purity monomer of a NexP-hGH protein, which is a long-acting human growth hormone, using anion-exchange resin chromatography; and a monomer of a NexP-hGH protein prepared by the method.

Inventors:

AHN JEE WON (KR)
KANG GIL BU (KR)
JUN CHANG BONG (KR)
LEE DONG EOK (KR)
YU JUNG MIN (KR)
CHOI EUN YOUNG (KR)
KIM KYUNG HWA (KR)
KIM EUN YOUNG (KR)
CHO SUNG YU (KR)
PARK YOUNG JOON (KR)
KIM KI WAN (KR)
LEE YOON JUNG (KR)
PARK SOON JAE (KR)

Application Number:

PCT/KR2013/010630

Publication Date:

May 30, 2014

Filing Date:

November 21, 2013

Export Citation:

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Assignee:

CJ CHEILJEDANG CORP (KR)
ALTEOGEN INC (KR)

International Classes:

C07K19/00; C07K1/18; C07K14/61

Domestic Patent References:

WO1999062936A1

1999-12-09

Foreign References:

KR101183262B1	2012-09-14
KR20120013359A	2012-02-14
US20080058507A1	2008-03-06

Other References:

ZHANG, C. ET AL.: "Genetic engineering strategies for purification of recombinant proteins from canola by anion exchange chromatography : an example of beta-glucuronidase.", BIOTECHNOL. PROG., vol. 17, no. 1, 2 January 2001 (2001-01-02), pages 161 - 167
CHO, E. K. ET AL.: "ATP-independent thermoprotective activity of Nicotian a tabacum heat shock protein 70 in Escherichia coli.", J. BIOCHEM. MOL. BIOL., vol. 40, no. 1, 31 January 2007 (2007-01-31), pages 107 - 112

Attorney, Agent or Firm:

SON, MIN (KR)
손민 (KR)

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